Results 261 to 270 of about 160,647 (335)

[308] PROTECTION AGAINST PHALLOIDIN HEPATOTOXICITY USING A SEMISYNTHETIC CHOLIC ACID DERIVATIVE, BALU-1

, 2007
Elisa Herráez, Rocı́o I.R. Macı́as, José Vázquez‐Tato, Cinta Hierro, Alba G. Blazquez, P. Martinez-Becerra, Francisco Jiménez Jiménez, F. Gonzalez-San Martin, José J.G. Marı́n   +8 more
openalex   +1 more source

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Mitigative effects of Otilonium Bromide on methotrexate-induced hepatic damage in rats. [PDF]

BMC Res Notes
Arı M, Erdogan MA, Erbaş O.
europepmc   +1 more source

Protective effects of Annona muricata ethanolic leaf extract against Dimethylnitrosamine (DMN)-Induced Hepatotoxicity.

, 2014
Iosr Journals, Usunomena Usunobun
openalex   +1 more source

Hepatic fibrosis in patients diagnosed with rheumatoid arthritis and psoriatic arthritis receiving methotrexate: A cross‐sectional analysis using transient elastography

Rheumatology &Autoimmunity, EarlyView.
Hepatic fibrosis and metabolic syndrome are more prevalent in PsA patients treated with methotrexate, compared to RA patients. Metabolic syndrome is associated with the risk of hepatic fibrosis in patients diagnosed with PsA and RA even after adjustment forcumulative methotrexate exposure.
Ratchaya Lertnawapan, Soonthorn Chonprasertsuk, Sith Siramolpiwat, Kanon Jatuworapruk   +3 more
wiley   +1 more source

Mechanism of hepatotoxicity induced by ethanol extract of <i>Emilia sonchifolia</i> (L.) DC revealed by proteomics and metabolomics. [PDF]

Front Pharmacol
Chen G, Luo Q, Song Z, Zheng P, Liu X, Tang T.   +5 more
europepmc   +1 more source

PHARMACOLOGICAL EVALUATION OF BOSWELLIA SERRATA AGAINST ISONIAZID-RIFAMPIN INDUCED HEPATOTOXICITY IN LABORATORY RATS

Amisha D. Randhir1*, Dr. Amita B. Dongare2, Ms. Ashlesha S. Gaikwad3
openalex   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

Rare Metals, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang, Zhiqiang Wang, Tong Zhang, Shicheng Qiu, Guang Yang, Yanzheng Gao, Xiaofeng Lian, Xin Peng   +7 more
wiley   +1 more source

Quinic acid attenuates arsenic-induced hepatic injury and hyperglycemia in mice via GLUT2 upregulation and suppression of oxidative stress and inflammation. [PDF]

Sci Rep
Aghamirzadeh SD, Khodayar MJ, Matin M, Rezaie A, Moosavi M.   +4 more
europepmc   +1 more source

Ligand‐Driven Optimization of Iron Oxide Nanoprobes for In Vivo MRI Enhancement at Ultra‐High Field

Small, EarlyView.
Ligand‐tailored iron oxide nanoparticles reveal how surface chemistry controls T2 relaxivity and in vivo performance in ultra‐high‐field MRI. Systematic variation of hydrophilicity and charge across five coatings modulated r2 by up to 333 mm−1 s−1, with chemical properties, rather than shell thickness, dictating magnetic dephasing and enabling reliable
Pelayo García‐Acevedo, María Luz Alonso‐Alonso, Sara Ortega‐Espina, Manuel Bañobre‐López, Yolanda Piñeiro, Ramón Iglesias‐Rey, José Rivas   +6 more
wiley   +1 more source