Results 201 to 210 of about 7,493 (302)

Antiseizure Treatments and Liver Injury: Expect (and Prevent) the Unexpected. [PDF]

Epilepsy Curr
Bunch M, Klocke S, Woodrich N, Barritt AS, Eyal S.   +4 more
europepmc   +1 more source

Diagnostic challenges in drug-induced liver injury. [PDF]

Clin Liver Dis (Hoboken)
Hayashi PH, Hoofnagle JH.
europepmc   +1 more source

What anabolic–androgenic steroids reveal about the limits of current harm reduction models

Addiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski, Jason M. Nagata, Suzanne Nielsen   +2 more
wiley   +1 more source

Editorial: Acute liver injury and repair: cellular and molecular mechanisms. [PDF]

Front Cell Dev Biol
Lin X, Shi S, Chen L, Gao P, Yang L.
europepmc   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Systematic analysis of hepatotoxicity: combining literature mining and AI language models. [PDF]

Front Artif Intell
Bauer C, Duc Dang LT, van den Beucken T, Schuchhardt J, Herwig R.   +4 more
europepmc   +1 more source

Triptolide capsule enables proteinuria reduction and renal stabilization in advanced alport syndrome beyond standard therapy

Rheumatology &Autoimmunity, EarlyView.
Zhuo‐ran Song, Na Li, Yang Li, Hong Zhang, Xu‐jie Zhou   +4 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Measuring Propidium Iodide Brightness as a Function of Viability: A High‐Throughput Quantitative Assessment of Hepatic Spheroids

Artificial Organs, EarlyView.
The graphical abstract illustrates our rapid PI‐based spheroid viability assay: hepatocyte spheroids are formed and stained with AO/PI, imaged after a 15‐min incubation, and analyzed for PI brightness normalized to area. This metric correlates strongly with functional urea/DNA output, validating PI intensity as a fast, reliable indicator of spheroid ...
Michael G. Megaly, Diane Tobolt, Bat‐Erdene Namsrai, Benjamin Fisher, Anthony An‐Fa Dahm Chen, Joseph Sushil Rao, Srivasupradha Ramesh, Anudari Chimedtseren, Mark Clemens, Charles Y. Lee, John C. Bischof, Erik B. Finger   +11 more
wiley   +1 more source

Idiosyncratic Warfarin-Induced Hepatocellular Injury: A Reversible and Uncommon Occurrence. [PDF]

Cureus
Al-Anbagi U, Elmabrouk AO, Elimam AA, Awadalla BM, Sharif M, Al Hariri B, Nashwan AJ, Noor Illahi M.   +7 more
europepmc   +1 more source