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2015
This chapter focuses on the signaling pathways involved in the synthesis of hepcidin, the iron hormone, and discusses the pathophysiological consequences of genetic and nongenetic disruption of its regulation. Hepcidin acts as the principal physiological inhibitor of iron flux into the bloodstream by inhibiting its receptor, the iron exporter ...
Vecchi C., Pietrangelo A.
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This chapter focuses on the signaling pathways involved in the synthesis of hepcidin, the iron hormone, and discusses the pathophysiological consequences of genetic and nongenetic disruption of its regulation. Hepcidin acts as the principal physiological inhibitor of iron flux into the bloodstream by inhibiting its receptor, the iron exporter ...
Vecchi C., Pietrangelo A.
openaire +1 more source
The role of the iron homeostasis mechanism is summarized in this article. Iron plays an important role in managing bodily functions such as growth and development, and makes haemoglobin, and some hormones. Hepcidin acts differently in different conditions; if the body needs more oxygen, the hepcidin levels decrease allowing iron to enter the plasma and
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Hepcidins in amphibians and fishes: Antimicrobial peptides or iron-regulatory hormones?
Developmental and Comparative Immunology, 2006Jishu Shi
exaly
Mini-Hepcidins Prevent Iron Overload In A Mouse Model of Hereditary Hemochromatosis
Blood, 2011Elizabeta Nemeth, Tomas Ganz
exaly