Results 1 to 10 of about 22,371 (222)
Exploring the therapeutic potential of recombinant bovine β-defensins for antimicrobial and anti-inflammatory functions in sepsis management [PDF]
Veterinary Researchβ-defensins are multifunctional peptides of the host immune system involved in responses to infectious diseases. We investigated the potential of five recombinant proteins based on bovine β-defensins (bovine neutrophil β-defensins (BNBD) 1, 2, 3, and 4 ...
Cristina Saubi +7 more
doaj +2 more sources
Understanding the roles of gingival beta-defensins
Journal of Oral Microbiology, 2012 Gingival epithelium produces β-defensins, small cationic peptides, as part of its contribution to the innate host defense against the bacterial challenge that is constantly present in the oral cavity.
Ulvi Kahraman Gursoy, Eija Könönen
exaly +3 more sources
In-Silico Tool for Predicting, Scanning, and Designing Defensins
Frontiers in Immunology, 2021 Defensins are host defense peptides present in nearly all living species, which play a crucial role in innate immunity. These peptides provide protection to the host, either by killing microbes directly or indirectly by activating the immune system.
Dilraj Kaur +5 more
doaj +1 more source
Defensins as a promising class of tick antimicrobial peptides: a scoping review
Infectious Diseases of Poverty, 2022 Background Ticks are hematophagous parasites that transmit an extensive range of pathogens to their vertebrate hosts. Ticks can destroy invading microorganisms or alleviate infection via their rudimentary but orchestrated innate immune system ...
Jiahui Wu +9 more
doaj +1 more source
Variations in the interaction of human defensins with Escherichia coli: Possible implications in bacterial killing. [PDF]
PLoS ONE, 2017 Human α and β-defensins are cationic antimicrobial peptides characterized by three disulfide bonds with a triple stranded β-sheet motif. It is presumed that interaction with the bacterial cell surface and membrane permeabilization by defensins is an ...
Basil Mathew, Ramakrishnan Nagaraj
doaj +1 more source
Respiratory Research, 2023 Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder associated with a 5–tenfold decrease in lung levels of alpha-1-antitrypsin (AAT) and an increased risk for obstructive lung disease.
Jungnam Lee +5 more
doaj +1 more source
International Journal of Infectious Diseases, 2023 Objectives: Nosocomial ventriculitis is a difficult infectious condition to diagnose given that typical cerebral spinal fluid (CSF) parameters, commonly used in the diagnosis of meningitis, lack sensitivity and specificity in nosocomial ventriculitis ...
James B. Doub
doaj +1 more source
Microbiology Spectrum, 2023 The intestinal microbiota is at the interface between the host and its environment and thus under constant exposure to host-derived and external modulators.
Fabiola Puértolas-Balint +1 more
doaj +1 more source
Increased expression and levels of human β defensins (hBD2 and hBD4) in adults with dental caries
Journal of Health Sciences, 2013 Introduction: Defensins are small anti-microbial peptides produced by epithelial cells. These peptides have a broad range of actions against microorganisms, including Gram-positive and Gram-negative bacteria.Human defensins are classifi ed into two ...
Girolamo Jose Barrera +4 more
doaj +3 more sources
FUNCTIONAL EFFECTS OF θ-DEFENSINS FROM BLOOD LEUKOCYTES OF BABOON PAPIO HAMADRYAS
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Aim. Study the functional properties of cationic antimicrobial peptides 0-defensins isolated from baboon Papio hamadryas blood leukocytes. Materials and methods.
E. V. Tsvetkova +5 more
doaj +1 more source