Results 11 to 20 of about 28,067 (241)
Defensins in periodontal health
Indian Journal of Dental Research, 2015 Defensins are abundant and widely distributed peptides in human and animal tissues that are involved in host defence. Defensins not only have the ability to strengthen the innate immune system but can also enhance the adaptive immune system by chemotaxis
Taran Bedi +2 more
doaj +4 more sources
Veterinary Immunology and Immunopathology, 2008 Modulation of defensin expression may be one way to improve animal health and to reduce zoonotic diseases. Defensins are small, cationic, and amphipathic cysteine-rich antibiotic peptides found in plants, insects, mammals and birds. Whereas alpha- and theta-defensins appear to be absent in birds, several beta-defensins have been isolated from avian ...
van Dijk, A. +2 more
openaire +5 more sources
Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients [PDF]
Journal of Immunology Research, 2016 Hepatitis C virus (HCV) is the major etiological agent of human non-A and non-B hepatitis, affecting around 180 million people worldwide. Defensins, small cysteine-rich cationic peptides, are shown to have potent antibacterial, antiviral, and antifungal ...
Ehab H. Mattar +4 more
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Role of defensins in immunothrombosis
Rheumatology & AutoimmunityThe interaction between innate immunity and coagulation is essential in thrombotic diseases, but the molecular links remain unclear. Neutrophils are key players, releasing mediators such as defensins, which are small cationic peptides with antimicrobial ...
Yuebing Wang +7 more
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Antiplasmodial activity is an ancient and conserved feature of tick defensins
Frontiers in Microbiology, 2016 Ancestral sequence reconstruction has been widely used to test evolution-based hypotheses. The genome of the European tick vector, Ixodes ricinus, encodes for defensin peptides with diverse antimicrobial activities against distantly related pathogens ...
Alejandro Cabezas-Cruz +9 more
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Modelling study of dimerization in mammalian defensins [PDF]
BMC Bioinformatics, 2006 Background Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes.
Verma Chandra, Suresh Anita
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, 2013 The term defensin relates to a set of host defense peptides (HDPs)in vertebrates, invertebrates, plants, and molds that display structural similarities based on a cystine stabilized antiparallel bet-sheetcore, with an alpha-helical stretch also present in some membrers, Defensins of different origins exhibit structural and functional similarities, with
ANTCHEVA, Nikolinka +2 more
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Understanding the roles of gingival beta-defensins [PDF]
Journal of Oral Microbiology, 2012 Gingival epithelium produces β-defensins, small cationic peptides, as part of its contribution to the innate host defense against the bacterial challenge that is constantly present in the oral cavity.
Ulvi Kahraman Gursoy +1 more
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Zdorovʹe Rebenka, 2012 This review presents the main systemic actions of defensins. Special attention is paid to modulatory effects of defensins on the processes of inflammation and immune response.
A.Ye. Abaturov
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Defensins: antifungal lessons from eukaryotes [PDF]
Frontiers in Microbiology, 2014 Over the last years, antimicrobial peptides (AMPs) have been the focus of intense research towards the finding of a viable alternative to current antifungal drugs.
Patrícia M. Silva +2 more
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