Results 1 to 10 of about 37,059 (248)

Comparative analysis of defensin expression in Hyalomma asiaticum ticks exposed to Staphylococcus aureus and Escherichia coli [PDF]

Frontiers in Veterinary Science
BackgroundHyalomma asiaticum, which acts as a vector of zoonotic pathogens, relies on its innate immune system for defense.MethodsUnfed adult female H.
Zhen Ma, Depeng Yang, Tingxiang Luo, Sen Yang, Wenxiu Hu, Qiya Wu, Zhengxiang Hu, Yongchang Li, Yongchang Li, Yongchang Li, Yongchang Li, Yongchang Li, Yang Zhang, Yang Zhang, Yang Zhang, Yang Zhang, Yang Zhang, Wei Zhang, Wei Zhang, Wei Zhang, Wei Zhang, Bayinchahan Gailike, Bayinchahan Gailike, Bayinchahan Gailike, Bayinchahan Gailike, Qingyong Guo, Qingyong Guo, Qingyong Guo, Qingyong Guo, Xiaoyun Mi, Ercha Hu, Ercha Hu, Ercha Hu, Ercha Hu, Ercha Hu, Caishan Li   +35 more
doaj   +2 more sources

Mosquito Antimicrobial Peptides: Molecular Diversity, Mechanisms of Action, and Translational Potential [PDF]

Current Issues in Molecular Biology
Mosquito antimicrobial peptides (AMPs) contribute to innate defense against bacteria, fungi, parasites, and, in some experimental contexts, arboviruses.
Yijie Xiao, Xinhao Li, Huchen Qin, Jinqian Li, Zhenxia Ma, Xiaolong Su, Li Gao, Lianghua Wang   +7 more
doaj   +2 more sources

AhR Activation Transcriptionally Induces Anti-Microbial Peptide Alpha-Defensin 1 Leading to Reversal of Gut Microbiota Dysbiosis and Colitis

Gut Microbes
Alpha-defensin 1 is a small antimicrobial peptide that acts as the first line of defense against pathogens. It is induced following microbial cues and inflammatory signals in neutrophils and Paneth cells in the small intestine, which suggests that it ...
Prakash Nagarkatti, Yin Zhong, Manikandan Palrasu   +2 more
exaly   +3 more sources

A Novel Approach on Leukodepletion Filters: Investigation of Synergistic Anticancer Effect of Purified α-Defensins and Nisin [PDF]

Advanced Pharmaceutical Bulletin, 2021
Purpose: There are number of reports available regarding defensins activity against mammalian cells besides their antimicrobial and immune regulatory activities.
Niloofar Sasani, Rasoul Roghanian, Giti Emtiazi, Afsaneh Aghaie   +3 more
doaj   +1 more source

Roles of Different β-Defensins in the Human Reproductive System: A Review Study

American Journal of Men's Health, 2023
Human β-defensins (hBDs) are cationic peptides with an amphipathic spatial shape and a high cysteine content. The members of this peptide family have been found in the human body with various functions, including the human reproductive system. Of among β-
Farzaneh Fesahat, Amir Masoud Firouzabadi, Hadi Zare-Zardini, Maryam Imani   +3 more
doaj   +1 more source

Cloning and Expression of β-Defensin from Soiny Mullet (Liza haematocheila), with Insights of its Antibacterial Mechanism. [PDF]

PLoS ONE, 2016
Beta-defensins are important part of innate immunity of fish, which are the first defense line against invading pathogens. In this study, the β-defensin (Lhβ-defensin) gene was cloned from spleen tissue of soiny mullet (Liza haematocheila).
Zhitao Qi, Wei Xu, Fancui Meng, Qihuan Zhang, Chenglung Chen, Rong Shao   +5 more
doaj   +1 more source

Dysregulation of human beta-defensin-3 expression in the peripheral blood of patients with sepsis

SAGE Open Medicine, 2021
Objectives: Sepsis is a serious medical condition caused by the body’s systemic inflammatory response to infections. The antimicrobial peptides, human beta-defensins, play a key role in modulating host immune responses, and aberrant expression of human ...
Noura Al Mansour, Ghada Al-Kafaji, Ali Al Mahmeed, Khalid M Bindayna   +3 more
doaj   +1 more source

Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota

Scientific Reports, 2023
Nonalcoholic steatohepatitis (NASH) is a chronic liver disease characterized by fibrosis that develops from fatty liver. Disruption of intestinal microbiota homeostasis, dysbiosis, is associated with fibrosis development in NASH. An antimicrobial peptide
Shunta Nakamura, Kiminori Nakamura, Yuki Yokoi, Yu Shimizu, Shuya Ohira, Mizu Hagiwara, Zihao Song, Li Gan, Tomoyasu Aizawa, Daigo Hashimoto, Takanori Teshima, Andre J. Ouellette, Tokiyoshi Ayabe   +12 more
doaj   +1 more source

Exploring the potential role of defensins in differential vector competence of body and head lice for Bartonella quintana

Parasites & Vectors, 2023
Background The body and head lice of humans are conspecific, but only the body louse functions as a vector to transmit bacterial pathogens such as Bartonella quintana. Both louse subspecies have only two antimicrobial peptides, defensin 1 and defensin 2.
Kyungjae Andrew Yoon, Do Eun Lee, Si Hyeock Lee, Ju Hyeon Kim   +3 more
doaj   +1 more source

Antimicrobial Properties and Mode of Action of Cryptdin-4, a Mouse α-Defensin Regulated by Peptide Redox Structures and Bacterial Cultivation Conditions

Antibiotics, 2023
Cryptdin-4 (crp4) is an enteric α-defensin derived from mice, and is a main mediator of immunity to oral infections and a determinant of the composition of the intestinal microbiota.
Yi Wang, Yuchi Song, Shaonan Yan, Rina Hiramine, Yuki Ohnishi, Yuki Yokoi, Kiminori Nakamura, Takashi Kikukawa, Tokiyoshi Ayabe, Tomoyasu Aizawa   +9 more
doaj   +1 more source