Results 11 to 20 of about 37,059 (248)
Airway β-Defensin-1 Protein Is Elevated in COPD and Severe Asthma
Background. Innate immune antimicrobial peptides, including β-defensin-1, promote the chemotaxis and activation of several immune cells. The role of β-defensin-1 in asthma and chronic obstructive pulmonary disease (COPD) remains unclear. Methods. Induced
Katherine J. Baines +7 more
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Molecular characterization of a defensin gene from a hard tick, Dermacentor silvarum
Background Ticks are distributed worldwide and considered as vectors of many human diseases. Tick defensins, a family of antimicrobial peptides, form the first line of defense against pathogens.
Juanjuan Wang +4 more
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False-negative synovial alpha-defensin
We present a case of chronic periprosthetic hip infection diagnosed using the Musculoskeletal Infection Society criteria as the gold standard. The alpha-defensin test was falsely negative.
Jake R. Adams, MD, Adam J. Schwartz, MD
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Abstract: Defensins are a family of small, variably cationic proteins which are highly abundant in the granules of mammalian phagocytes. Three defensins, HNP‐1, 2, and 3, comprise 30–50% of total protein in azurophil granules of human neutrophils. Some defensins are broadly antimicrobial, antiviral and cytotoxic, while others are chemotactic, opsonic,
T, Ganz, M E, Selsted, R I, Lehrer
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Evidence of convergent evolution in humans and macaques supports an adaptive role for copy number variation of the β-defensin-2 gene. [PDF]
β-defensins are a family of important peptides of innate immunity, involved in host defense, immunomodulation, reproduction, and pigmentation. Genes encoding β-defensins show evidence of birth-and-death evolution, adaptation by amino acid sequence ...
J. V. Solnick (2176576) +9 more
core +5 more sources
Sepsis is a leading cause of mortality and morbidity in the critical illness. Multiple immune inflammatory processes take part in the pathogenesis of sepsis. Defensins are endogenous antimicrobial peptides with three disulphide bonds created by six cysteine residues.
Xie, Guo-Hao +3 more
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Data_Sheet_1_β-defensin-4 as an endogenous biomarker in cows with mastitis.docx
IntroductionDefensins are peptides with antimicrobial and immunomodulatory effects. Their concentration could be altered during infections and thus provide information on the prognosis and course of the disease.
Anneke Fischer (14835181) +2 more
core +1 more source
The black soldier fly (BSF), Hermetia illucens L. (Diptera: Stratiomyidae), has a great bioconversion potential and ability to develop on diverse substrates.
Valentina Candian +2 more
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Defensin-driven viral evolution. [PDF]
Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralization of
Youngmee Sul +13 more
core +2 more sources
The literature review, according to recent publications, systematizes modern ideas about new biochemical markers of bronchopulmonary pathology, namely chronic obstructive pulmonary disease, chronic bronchitis and bronchial asthma.
E. A. Kurtukov, Yu. I. Ragino
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