Results 11 to 20 of about 37,059 (248)

Airway β-Defensin-1 Protein Is Elevated in COPD and Severe Asthma

open access: yesMediators of Inflammation, 2015
Background. Innate immune antimicrobial peptides, including β-defensin-1, promote the chemotaxis and activation of several immune cells. The role of β-defensin-1 in asthma and chronic obstructive pulmonary disease (COPD) remains unclear. Methods. Induced
Katherine J. Baines   +7 more
doaj   +2 more sources

Molecular characterization of a defensin gene from a hard tick, Dermacentor silvarum

open access: yesParasites & Vectors, 2015
Background Ticks are distributed worldwide and considered as vectors of many human diseases. Tick defensins, a family of antimicrobial peptides, form the first line of defense against pathogens.
Juanjuan Wang   +4 more
doaj   +2 more sources

False-negative synovial alpha-defensin

open access: yesArthroplasty Today, 2017
We present a case of chronic periprosthetic hip infection diagnosed using the Musculoskeletal Infection Society criteria as the gold standard. The alpha-defensin test was falsely negative.
Jake R. Adams, MD, Adam J. Schwartz, MD
doaj   +2 more sources

Defensins [PDF]

open access: yesClinical Immunology Newsletter, 1987
Abstract: Defensins are a family of small, variably cationic proteins which are highly abundant in the granules of mammalian phagocytes. Three defensins, HNP‐1, 2, and 3, comprise 30–50% of total protein in azurophil granules of human neutrophils. Some defensins are broadly antimicrobial, antiviral and cytotoxic, while others are chemotactic, opsonic,
T, Ganz, M E, Selsted, R I, Lehrer
openaire   +2 more sources

Evidence of convergent evolution in humans and macaques supports an adaptive role for copy number variation of the β-defensin-2 gene. [PDF]

open access: yes, 2014
β-defensins are a family of important peptides of innate immunity, involved in host defense, immunomodulation, reproduction, and pigmentation. Genes encoding β-defensins show evidence of birth-and-death evolution, adaptation by amino acid sequence ...
J. V. Solnick (2176576)   +9 more
core   +5 more sources

Defensins and Sepsis [PDF]

open access: yesBioMed Research International, 2014
Sepsis is a leading cause of mortality and morbidity in the critical illness. Multiple immune inflammatory processes take part in the pathogenesis of sepsis. Defensins are endogenous antimicrobial peptides with three disulphide bonds created by six cysteine residues.
Xie, Guo-Hao   +3 more
openaire   +2 more sources

Data_Sheet_1_β-defensin-4 as an endogenous biomarker in cows with mastitis.docx

open access: yes, 2023
IntroductionDefensins are peptides with antimicrobial and immunomodulatory effects. Their concentration could be altered during infections and thus provide information on the prognosis and course of the disease.
Anneke Fischer (14835181)   +2 more
core   +1 more source

Immune Responses of the Black Soldier Fly Hermetia illucens (L.) (Diptera: Stratiomyidae) Reared on Catering Waste

open access: yesLife, 2023
The black soldier fly (BSF), Hermetia illucens L. (Diptera: Stratiomyidae), has a great bioconversion potential and ability to develop on diverse substrates.
Valentina Candian   +2 more
doaj   +1 more source

Defensin-driven viral evolution. [PDF]

open access: yes, 2020
Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralization of
Youngmee Sul   +13 more
core   +2 more sources

Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem

open access: yesСибирский научный медицинский журнал, 2020
The literature review, according to recent publications, systematizes modern ideas about new biochemical markers of bronchopulmonary pathology, namely chronic obstructive pulmonary disease, chronic bronchitis and bronchial asthma.
E. A. Kurtukov, Yu. I. Ragino
doaj   +1 more source

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