Results 31 to 40 of about 42,072 (251)
Medicinal Potentialities of Plant Defensins: A Review with Applied Perspectives
Medicines, 2019 Plant-based secondary metabolites with medicinal potentialities such as defensins are small, cysteine-rich peptides that represent an imperative aspect of the inherent defense system.
Nida Ishaq +2 more
doaj +1 more source
Frontiers in Immunology, 2020 In addition to their established functions in host defense, accumulating evidence has suggested an emerging role for antimicrobial proteins (AMPs) in shaping commensal microbiota.
Jiayao Ou +11 more
doaj +1 more source
Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients
Journal of Immunology Research, 2016 Hepatitis C virus (HCV) is the major etiological agent of human non-A and non-B hepatitis, affecting around 180 million people worldwide. Defensins, small cysteine-rich cationic peptides, are shown to have potent antibacterial, antiviral, and antifungal ...
Ehab H. Mattar +4 more
doaj +1 more source
Antiplasmodial activity is an ancient and conserved feature of tick defensins
Frontiers in Microbiology, 2016 Ancestral sequence reconstruction has been widely used to test evolution-based hypotheses. The genome of the European tick vector, Ixodes ricinus, encodes for defensin peptides with diverse antimicrobial activities against distantly related pathogens ...
Alejandro Cabezas-Cruz +9 more
doaj +1 more source
Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]
, 2015 Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core +1 more source
Cyclic Peptides as Novel Therapeutic Microbicides: Engineering of Human Defensin Mimetics
Molecules, 2017 Cyclic peptides are receiving significant attention thanks to their antimicrobial activity and high serum stability, which is useful to develop and design novel antimicrobial agents.
Annarita Falanga +6 more
doaj +1 more source
Antifungal Plant Defensins: Mechanisms of Action and Production
Molecules, 2014 Plant defensins are small, cysteine-rich peptides that possess biological activity towards a broad range of organisms. Their activity is primarily directed against fungi, but bactericidal and insecticidal actions have also been reported.
Kim Vriens +2 more
doaj +1 more source
Defensins: A Double-Edged Sword in Host Immunity
Frontiers in Immunology, 2020 Defensins are a major family of host defense peptides expressed predominantly in neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted immunomodulatory functions have been extensively studied, cementing their role in ...
Dan Xu, Wuyuan Lu
doaj +1 more source
BioMed Research International, 2014 Sepsis is a leading cause of mortality and morbidity in the critical illness. Multiple immune inflammatory processes take part in the pathogenesis of sepsis. Defensins are endogenous antimicrobial peptides with three disulphide bonds created by six cysteine residues.
Xie, Guo-Hao +3 more
openaire +2 more sources
A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility [PDF]
, 2013 peer-reviewedMastitis is an inflammation-driven disease of the bovine mammary gland that occurs in response to physical damage or infection and is one of the most costly production-related diseases in the dairy industry worldwide.
Alan eFahey +7 more
core +2 more sources