Results 31 to 40 of about 28,067 (241)
Antifungal Plant Defensins: Mechanisms of Action and Production
Molecules, 2014 Plant defensins are small, cysteine-rich peptides that possess biological activity towards a broad range of organisms. Their activity is primarily directed against fungi, but bactericidal and insecticidal actions have also been reported.
Kim Vriens +2 more
doaj +1 more source
Artificial β-defensin based on a minimal defensin template
Biochemical Journal, 2009 We have designed and chemically synthesized an artificial β-defensin based on a minimal template derived from the comparative analysis of over 80 naturally occurring sequences. This molecule has the disulfide-bridged β-sheet core structure of natural β-defensins and shows a robust salt-sensitive antimicrobial activity against bacteria and yeast, as ...
ANTCHEVA, Nikolinka +8 more
openaire +4 more sources
Reproductive Biology and Endocrinology, 2006 Background beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are predominantly expressed in the male reproductive tract and have roles in non-immunological
French Frank S +5 more
doaj +1 more source
Egyptian Rheumatology and Rehabilitation, 2020 Background Behcet’s disease (BD) is associated with uveitis, oral ulcers, genital ulcers and arthritis. Enhanced activity of innate immunity components, such as neutrophils, natural killer (NK) cells and endothelial cells, is a prominent feature of BD ...
Reham M. Shaat +4 more
doaj +1 more source
Defensins: A Double-Edged Sword in Host Immunity
Frontiers in Immunology, 2020 Defensins are a major family of host defense peptides expressed predominantly in neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted immunomodulatory functions have been extensively studied, cementing their role in ...
Dan Xu, Wuyuan Lu
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Ixodes ricinus defensins attack distantly-related pathogens
, 2015 Contribution: Study design and data analysisInternational audienceAntimicrobial peptides are ubiquitous components of eukaryotic innate immunity. Defensins are a well-known family of antimicrobial peptides, widely distributed in ticks, insects, plants ...
Rahnamaeian, Mohammad +17 more
core +2 more sources
Functional Insights From the Evolutionary Diversification of Big Defensins
Frontiers in Immunology, 2020 Big defensins are antimicrobial polypeptides believed to be the ancestors of β-defensins, the most evolutionary conserved family of host defense peptides (HDPs) in vertebrates.
Marco Gerdol +5 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source