Results 41 to 50 of about 28,067 (241)

β-defensins and the epididymis: contrasting influences of prenatal, postnatal, and adult scenarios

open access: yesAsian Journal of Andrology, 2016
β-defensins are components of host defense, with antimicrobial and pleiotropic immuno-modulatory properties. Research over the last 15 years has demonstrated abundant expression of a variety of β-defensins in the postnatal epididymis of different species.
Camilla M Ribeiro   +3 more
doaj   +1 more source

Plant Defensins from a Structural Perspective

open access: yes, 2020
Plant defensins form a family of proteins with a broad spectrum of protective activities against fungi, bacteria, and insects. Furthermore, some plant defensins have revealed anticancer activity.
Irina V. Nesmelova   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A systematic structural comparison of all solved small proteins deposited in PDB. The effect of disulfide bonds in protein fold

open access: yesComputational and Structural Biotechnology Journal, 2021
Defensins are small proteins, usually ranging from 3 to 6 kDa, amphipathic, disulfide-rich, and with a small or even absent hydrophobic core. Since a hydrophobic core is generally found in globular proteins that fold in an aqueous solvent, the peculiar ...
Mariana H. Moreira   +3 more
doaj   +1 more source

Plant Defensins : Tissue Specific Expression Leading to Distinctive Functions [PDF]

open access: yes, 2019
Plant defensins are small, cysteine-rich cationic antimicrobial peptides that possess biological activity towards a broad range of pathogenic organisms.
Bhatnagar-Mathur, P   +3 more
core  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Research progress on anti-mycobacterial effect of mammal defensins

open access: yesSiliao yanjiu, 2022
Mammalian defencins are cationic peptides with antimicrobial activity produced by a variety of cells. They are divided into α-defencins, β-defencins and θ-defencins, which exert antimicrobial effects mainly by increasing the permeability of bacterial ...
KANG Jing-jing   +5 more
doaj  

Antifungal defensins and their role in plant defense

open access: yesFrontiers in Microbiology, 2014
Since the beginning of the 90’s lots of cationic plant, cysteine-rich antimicrobial peptides (AMP) have been studied. However, Broekaert only coined the term plant defensin in 1995, after comparison of a new class of plant antifungal peptides with known
Ariane eLacerda   +4 more
doaj   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

open access: yesAdvanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang   +15 more
wiley   +1 more source

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

open access: yesAnimal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu   +11 more
wiley   +1 more source

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