Results 41 to 50 of about 42,072 (251)
Reproductive Biology and Endocrinology, 2006 Background beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are predominantly expressed in the male reproductive tract and have roles in non-immunological
French Frank S +5 more
doaj +1 more source
Egyptian Rheumatology and Rehabilitation, 2020 Background Behcet’s disease (BD) is associated with uveitis, oral ulcers, genital ulcers and arthritis. Enhanced activity of innate immunity components, such as neutrophils, natural killer (NK) cells and endothelial cells, is a prominent feature of BD ...
Reham M. Shaat +4 more
doaj +1 more source
Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]
, 2018 Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard +156 more
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Symbiotic outcome modified by the diversification from 7 to over 700 nodule specific cysteine rich peptides [PDF]
, 2020 Legume-rhizobium symbiosis represents one of the most successfully co-evolved mutualisms. Within nodules, the bacterial cells undergo distinct metabolic and morphological changes and differentiate into nitrogen-fixing bacteroids.
Achom, Mingkee +4 more
core +1 more source
The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis [PDF]
, 2017 Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal disease of prematurity. Although the precise cause is not well understood, the main risk factors thought to contribute to NEC include prematurity, formula feeding, and bacterial ...
Bolock, Alexa M +2 more
core +2 more sources
Defensin-driven viral evolution.
PLoS Pathogens, 2020 Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralization of
Karina Diaz +7 more
doaj +1 more source
Functional Insights From the Evolutionary Diversification of Big Defensins
Frontiers in Immunology, 2020 Big defensins are antimicrobial polypeptides believed to be the ancestors of β-defensins, the most evolutionary conserved family of host defense peptides (HDPs) in vertebrates.
Marco Gerdol +5 more
doaj +1 more source
Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii [PDF]
, 2015 © 2015 Elsevier Inc. Fossil fuel emissions and changes in net land use lead to an increase in atmospheric CO 2 concentration and a subsequent decrease of ocean pH. Noticeable effects on organisms' calcification rate, shell structure and energy metabolism
Hardege, Jörg D. +3 more
core +2 more sources
Aggregation‐State Dynamics Drive Double Cooperativity Between Antimicrobial Peptides LL‐37 and HNP1
Angewandte Chemie, EarlyView.The double cooperative effect between LL‐37 and HNP1 arises from dynamic changes in their aggregation state. These LL‐37/HNP1 assemblies reorganize in a target‐dependent manner, suppressing activity toward mammalian cells while enabling potent antibacterial action.
Yuge Hou +9 more
wiley +2 more sources
β-defensins and the epididymis: contrasting influences of prenatal, postnatal, and adult scenarios
Asian Journal of Andrology, 2016 β-defensins are components of host defense, with antimicrobial and pleiotropic immuno-modulatory properties. Research over the last 15 years has demonstrated abundant expression of a variety of β-defensins in the postnatal epididymis of different species.
Camilla M Ribeiro +3 more
doaj +1 more source