Results 231 to 240 of about 326,443 (336)

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Breast cancer liver metastases and the impact of receptor expression on survival. [PDF]

Clin Exp Metastasis
Hansson E, Sundén M, Wadsten C, Rask G, Andersson A, Sund M, Hemmingsson O.   +6 more
europepmc   +1 more source

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma

International Journal of Cancer, EarlyView.
What's New? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang, Ken Yamaguchi, Kohei Hamada, Yuko Hosoe, Yuka Mise, Sachiko Kitamura, Zhihong Liu, Hairong Wei, Zhenhai Gao, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Rin Mizuno, Taito Miyamoto, Junzo Hamanishi, Masaki Mandai   +15 more
wiley   +1 more source

Potential Targets and Biomarkers of Radionuclide Therapy in Breast Cancer. [PDF]

Cancer Innov
Tan Y, Zeng C, Wang J, Ma F.
europepmc   +1 more source

From mechanism to phenotype: What fits in a basket trial

Epilepsia, EarlyView.
Kette D. Valente
wiley   +1 more source

Extracellular vesicle‐based vaccines and immunotherapeutics for treatment of cancer

Interdisciplinary Medicine, EarlyView.
This review highlights the innovative value of extracellular vesicles (EVs) as cancer vaccines and immunotherapy carriers. EVs have natural advantages such as low immunogenicity, high biocompatibility, stability, and precise targeting, enabling efficient delivery of tumor antigens (e.g., HER2, AFP) and immune stimulants (e.g., TLR ligands, cytokines ...
Lejia Tan, Haonan Xing, Fang Fang, Yuanyu Huang, Mei Lu   +4 more
wiley   +1 more source

Quantitative HER2 profiling on circulating tumor cells using an EpCAM-independent platform in metastatic breast cancer. [PDF]

Cancer Cell Int
Bayou N, Henretta S, Munoz-Arcos L, Molteni E, Gianni C, Serafini MS, Nicolò E, Pontolillo L, Pasto B, Gaudio HA, Manai M, Afghan MMK, Manohar J, Elemento O, Andreopoulou E, Cristofanilli M, Reduzzi C.   +16 more
europepmc   +1 more source

Adding pertuzumab to adjuvant therapy for high-risk HER2-positive early breast cancer in APHINITY: a GRADE analysis

, 2020
Alberto Zambelli, Giovanni Pappagallo, Paolo Marchetti   +2 more
openalex   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Exercise as Precision Medicine: Targeting HER2/CD44-Driven Therapy Resistance in Breast Cancer (A Mini Review). [PDF]

Integr Cancer Ther
Edalat Haghi FA, Koushkie Jahromi M.
europepmc   +1 more source