Results 211 to 220 of about 197,589 (314)

SiNuS: A comprehensive dataset for singular nuclei segmentation for <i>HER2</i> grading of breast cancer. [PDF]

Data Brief
Hossain MS, Rahman MS, Ahmed M.
europepmc   +1 more source

The Role of Primary Tumor Resection in De Novo Bone‐Only Metastatic Breast Cancer: A Propensity Score‐Matched Analysis

Journal of Surgical Oncology, EarlyView.
ABSTRACT Objective To evaluate the impact of primary tumor resection (PTR) on overall survival (OS) and cancer‐specific survival (CSS) in women with de novo bone‐only metastatic breast cancer (MBC). Methods Women diagnosed with de novo bone‐only metastatic breast cancer between 2010 and 2017 were identified from the Surveillance, Epidemiology, and End ...
Bin Wang, Shasha Liu, Zhidong Huang, Jinhui Wang, Xirui Zhou, Shuo Li, Jianan Chen, Hong Liu   +7 more
wiley   +1 more source

STARD10 promotes progression of HER2+ breast cancer and intracellular lipid metabolism via the cAMP/PKA/CREB1 signaling axis. [PDF]

Cancer Biol Ther
Liu S, Gao J, Niu Y, Dong X, Zhang Z, Teng X, Li Z, Zhang S, Meng Y, Gao MQ.   +9 more
europepmc   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

Exploring the Role of <i>HER1</i> and <i>HER2</i> Gene Variants in Breast Cancer Susceptibility: A Case-Control Study in Bangladesh. [PDF]

Health Sci Rep
Tabassum R, Abid AA, Shithi SSI, Islam S, Rafique URB, Shultana S, Mohiuddin M, Tanjum S, Haque MA.   +8 more
europepmc   +1 more source

Risk Factors Influencing Efficacy and Prognosis Evaluation of Neoadjuvant Systemic Therapy in Triple‐Positive Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT To identify the determinants of the response to neoadjuvant systemic therapy (NST) in triple‐positive breast cancer (TPBC), we retrospectively enrolled 520 patients with human epidermal growth factor receptor 2 (HER2)‐positive breast cancer who were treated at The First Affiliated Hospital of Chongqing Medical University between January 2015 ...
Lin‐Rui Miao, Hao Liu, Hai‐Ying Yu, Jian Chen, Ming‐Yu Yang, Ya‐Lan Zhang, Gang Tu, Ling‐Feng Tang   +7 more
wiley   +1 more source

Clinicopathological Characteristics, Prognosis, and Survival of HER2-Low Breast Cancer Patients Based on a Retrospective Cohort Study of 14,642 Patients. [PDF]

Cancers (Basel)
Sun W, Hou X, Yang Z, Li G, Zhang L, Wang Q, He X, Zhang X, Liu L, He C, Xu S.   +10 more
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Efficacy of Disitamab Vedotin in Treating HER2 2+/FISH-Bladder Cancer: A Case Report. [PDF]

Clin Case Rep
Jin ZR, Dong CY, Li YJ, Zou Y, Wang XM, Li HY, Wang G, Cui XN, Liu Y.   +8 more
europepmc   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source