Results 191 to 200 of about 197,589 (314)

HER2 Low Expression in Primary Male Breast Cancer

Katleen Nobbe,1 Melanie Erices-Leclercq,1 Frank Foerster,2,3 Robert Förster,4 Stephan E Baldus,5 Christian Rudlowski,1,6 Lars Schröder,7 Sabine Lubig1 1Breast Unit, Lutheran Hospital Bergisch Gladbach, Bergisch Gladbach, Germany; 2Department of ...
Schröder L, Erices-Leclercq M, Rudlowski C, Foerster F, Nobbe K, Baldus SE, Lubig S, Förster R   +7 more
core  

Impact of Reimbursement on the Utilisation of Gene Expression Profiles and Chemotherapy Decision‐Making in Dutch Breast Cancer Patients: A Population‐Based Study

International Journal of Cancer, EarlyView.
To avoid unnecessary treatment in breast cancer, several gene expression profiling tests have been developed to help clinicians identify patients who may not benefit from chemotherapy. This study examined the effect of reimbursement availability on the implementation of gene expression profiles using population‐based data from the Netherlands Cancer ...
Joyce Meijer, Nienke Hermanns, Rhodé Bijlsma, Hedwig M. Blommestein, Desiree H. J. G. van den Bongard, Thijs van Dalen, Paul J. van Diest, Caroline A. Drukker, Cristina Guerrero Paez, Aafke H. Honkoop, Agnes Jager, Linetta B. Koppert, Sabine C. Linn, Marissa C. van Maaren, Ester J. Siemerink, Laura J. van ’t, José H. Volders, Marie Jeanne Vrancken Peeters, Sabine Siesling   +18 more
wiley   +1 more source

Retrospective Analysis of HER2 Testing, Treatment Patterns, and Clinical Outcomes in Patients With Locally Advanced or Metastatic NSCLC With HER2 Mutations in France. [PDF]

Cancer Med
Debieuvre D, Macouillard P, Quantin X, Berktas M, Girard N, Audigier-Valette C, Filleron T, Musilli S, Bosquet L, Pérol M.   +9 more
europepmc   +1 more source

Clinical Implementation and Oncological Relevance of Molecular Profiling in Brain Metastases Patients—A Multicenter Retrospective Cohort Study

International Journal of Cancer, EarlyView.
While current guidelines recommend the analysis of established cancer driver genes in brain metastases, little is known about its real‐life implementation. This multicenter study revealed an upward trend in the profiling rates of surgically treated brain metastases over the past decade, with up to 60% of brain metastases samples undergoing analysis ...
Maria Nikolaeva, Jacopo Bellomo, Meltem Gönel, Vittorio Stumpo, Victor Egon Staartjes, Flavio Vasella, Kevin Akeret, André Sagerer, Anna Maria Zeitlberger, David Wasilewski, Christopher Krämer, Sven König, Julia Onken, Tareq Juratli, Alexander Köpp, Regina Reimann, Marcus Czabanka, Peter Vajkoczy, Ilker Y. Eyüpoglu, Oliver Bozinov, Michael Weller, Emilie Le Rhun, Luca Regli, Carlo Serra, Marian C. Neidert, Stefanos Voglis   +25 more
wiley   +1 more source

HER2-Low Gastric and Gastroesophageal Junction Adenocarcinoma: From Assessment to Treatment Strategies. [PDF]

Int J Mol Sci
Scurtu AG, Sala DT, Jung I, Bara T, Neagoe RM, Fülöp ZZ, Gurzu S.   +6 more
europepmc   +1 more source

Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival

International Journal of Cancer, EarlyView.
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li, Elaheh Zarean, Danmeng Lily Li, Yiyue Zhu, Shuai Li, Enes Makalic, Catriona McLean, Graham G. Giles, Roger L. Milne, Melissa C. Southey, Pierre‐Antoine Dugué   +10 more
wiley   +1 more source

MET Expression in Upper Gastrointestinal Adenocarcinoma: Prevalence, Prognostic Impact, and Implications for Anti‐MET Antibody‐Drug Conjugate Therapy

International Journal of Cancer, EarlyView.
ABSTRACT MET is an actionable receptor tyrosine kinase, and MET‐directed antibody–drug conjugates (ADCs) have recently entered clinical practice with FDA approval in non‐small cell lung cancer and are now being evaluated across gastrointestinal malignancies, with patient selection based on MET immunohistochemistry (IHC) 3+ membranous staining at ...
Tillmann Bedau, Thomas Zander, Hans Anton Schlößer, Hakan Alakus, Onur Mustafov, Reinhard Büttner, Christiane Bruns, Alexander Quaas   +7 more
wiley   +1 more source

The role of human microbiota in breast cancer pathogenesis and treatment

iMeta, EarlyView.
The human microbiota contributes to breast cancer pathogenesis and treatment response through interactions involving the oral, gut, and breast microbial niches. (Left) Multi‐site dysbiosis is characterized by altered microbial composition and abundance across different anatomical sites.
Jie Qiu, Xiaojia Wang, Man Li, Jing Guo, Shipeng Ning, Yi‐Zhou Gao, Xinyi Zhang, Xuli Meng, Yiding Chen, Yunxiang Zhou   +9 more
wiley   +1 more source

Two new <i>Vibrio diazotrophicus</i> strains isolated from deep-sea hydrothermal iron-rich microbial mats display unexpected metabolic capacities. [PDF]

FEMS Microbes
Michaudet L, Pouder E, Bienvenu N, Philippon X, Ménec M, Rouxel O, Cambon MA, Hervio-Heath D, Geslin C, Alain K, Mieszkin S.   +10 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source