Results 201 to 210 of about 48,877 (264)
Wildlife Biology, EarlyView.Overabundant populations of eastern grey kangaroos Macropus giganteus in peri‐urban areas pose ecological and social challenges. Current management strategies are often hindered by animal welfare and logistical concerns. This study aimed to assess stress responses of kangaroos to two contraceptive delivery methods.
Fabiola R. O. Silva +4 more
wiley +1 more source
Integrative Zoology, EarlyView.Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu +3 more
wiley +1 more source
Herb-drug interaction: The importance of communicating with primary care physicians. [PDF]
Australas Med J, 2015 Bhadra R, Ravakhah K, Ghosh RK.
europepmc +1 more source
Does the total consumption model apply to cannabis use?
Addiction, EarlyView.Abstract Aims To test whether the total consumption model and its extension, the theory of collectivity, apply to adolescent cannabis use. We estimated: (1) whether the distribution of cannabis use frequency was stable over time; (2) whether changes in average cannabis use were mirrored across consumption quantiles; and (3) whether higher average use ...
Thor Norström, Håkan Leifman
wiley +1 more source
Herb-Drug Interaction between the Traditional Hepatoprotective Formulation and Sorafenib on Hepatotoxicity, Histopathology and Pharmacokinetics in Rats. [PDF]
Molecules, 2017 Ting CT, Cheng YY, Tsai TH.
europepmc +1 more source
Allergy, EarlyView.This randomized, double‐blind, placebo‐controlled trial evaluated the effects of live probiotic and HT postbiotic B. longum CECT 7347 in adults with moderate–severe allergic rhinitis. Postbiotic supplementation for 8 weeks significantly reduced CSMS and dSS, exceeding the established CSMS MCID with a 33% greater improvement, when compared to placebo ...
Ana Cardoso +9 more
wiley +1 more source
Quantitative prediction and clinical evaluation of an unexplored herb-drug interaction mechanism in healthy volunteers. [PDF]
CPT Pharmacometrics Syst Pharmacol, 2015 Gufford BT +6 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr +10 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source