Herb–Drug Interaction of Red Ginseng Extract and Ginsenoside Rc with Valsartan in Rats [PDF]
Molecules, 2020 The purpose of this study was to investigate the herb−drug interactions involving red ginseng extract (RGE) or ginsenoside Rc with valsartan, a substrate for organic anion transporting polypeptide (OATP/Oatp) transporters.
Ji-Hyeon Jeon +7 more
doaj +4 more sources
Herb–Drug Interactions: Worlds Intersect with the Patient at the Center
Medicines, 2021 This review examines three bodies of literature related to herb–drug interactions: case reports, clinical studies, evaluations found in six drug interaction checking resources.
Mary Beth Babos +9 more
doaj +3 more sources
Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats [PDF]
Molecules, 2016 Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, and Fructus Gardeniae are often used alongside with clozapine (CLZ) for schizophrenia patients in order to reduce side effects and enhance therapeutic efficacy.
Dan-Dan Tian +4 more
doaj +2 more sources
Herb-Drug Interaction Between Sailuotong and Pitavastatin: A Systematic Pharmacokinetic Investigation and Mechanism Analysis [PDF]
Drug Design, Development and TherapyYing Zhang,* Huan Yi,* Hongtian Yang, Yuchen Song, Changying Ren, Xiang Li, Ying Zhang Beijing Key Laboratory of Pharmacology of Chinese Materia Medica, Institute of Basic Medical Sciences, Xiyuan Hospital, China Academy of Chinese ...
Zhang Y +6 more
doaj +2 more sources
Optimizing phenytoin therapy: a systematic review of clinically relevant food and herb interactions [PDF]
Frontiers in PharmacologyIntroductionPhenytoin, a widely prescribed anticonvulsant, presents clinical challenges due to its narrow therapeutic index and potential interactions with various foods, herbs, and medications.
Adriana Monserrath Orellana-Paucar +10 more
doaj +2 more sources
Herb-drug interaction resources: The PHYDGI database
Phytomedicine Plus, 2022 Background: According to the WHO, about 60% of the world's population currently uses traditional herbal remedies as complementary or alternative medicine and 80% of the population in developing countries depends almost totally on them for their primary ...
J. Perrot +6 more
doaj +1 more source
Planta Medica, 2012 fo r pe rs on al u se o nl y. U na ut ho riz ed d is tr ib ut io n is s tr ic tly p ro hi bi te d. Today it is very common for patients to take many medications simultaneously. This is particularly true for elderly patients who frequently take ten and more medications. With multiple prescribed medications, there are numerous potential drug interactions
Veronika, Butterweck, Hartmut, Derendorf
openaire +2 more sources
Current perspectives in herbal and conventional drug interactions based on clinical manifestations
Future Journal of Pharmaceutical Sciences, 2021 Background Herbs are an important source of pharmaceuticals. Herbs are traditionally used by millions of peoples for medicine, food and drink in developed and developing nations considering that they are safe.
Ajaykumar Rikhabchand Surana +3 more
doaj +1 more source
Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes [PDF]
, 2016 Cytochrome p450 (CYP450) enzymes are predominantly involved in Phase I metabolism of xenobiotics. In this study, the CYP450 isoforms involved in xanthotoxol metabolism were identified using recombinant CYP450s.
Cai, Jiqun +5 more
core +13 more sources
Enzyme Activity of Natural Products on Cytochrome P450
Molecules, 2022 Drug-metabolizing enzymes, particularly the cytochrome P450 (CYP450) monooxygenases, play a pivotal role in pharmacokinetics. CYP450 enzymes can be affected by various xenobiotic substrates, which will eventually be responsible for most metabolism-based ...
Hua-Li Zuo +7 more
doaj +1 more source