Herb–Drug Interaction of Red Ginseng Extract and Ginsenoside Rc with Valsartan in Rats [PDF]
Molecules, 2020 The purpose of this study was to investigate the herb−drug interactions involving red ginseng extract (RGE) or ginsenoside Rc with valsartan, a substrate for organic anion transporting polypeptide (OATP/Oatp) transporters.
Ji-Hyeon Jeon +7 more
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Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats [PDF]
Molecules, 2016 Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, and Fructus Gardeniae are often used alongside with clozapine (CLZ) for schizophrenia patients in order to reduce side effects and enhance therapeutic efficacy.
Dan-Dan Tian +4 more
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Herb-Drug Interaction Between Sailuotong and Pitavastatin: A Systematic Pharmacokinetic Investigation and Mechanism Analysis [PDF]
Drug Design, Development and TherapyYing Zhang,* Huan Yi,* Hongtian Yang, Yuchen Song, Changying Ren, Xiang Li, Ying Zhang Beijing Key Laboratory of Pharmacology of Chinese Materia Medica, Institute of Basic Medical Sciences, Xiyuan Hospital, China Academy of Chinese ...
Zhang Y +6 more
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Optimizing phenytoin therapy: a systematic review of clinically relevant food and herb interactions [PDF]
Frontiers in PharmacologyIntroductionPhenytoin, a widely prescribed anticonvulsant, presents clinical challenges due to its narrow therapeutic index and potential interactions with various foods, herbs, and medications.
Adriana Monserrath Orellana-Paucar +10 more
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Herb–Drug Interactions: Worlds Intersect with the Patient at the Center
Medicines, 2021 This review examines three bodies of literature related to herb–drug interactions: case reports, clinical studies, evaluations found in six drug interaction checking resources.
Mary Beth Babos +9 more
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Herb-drug interaction resources: The PHYDGI database
Phytomedicine Plus, 2022 Background: According to the WHO, about 60% of the world's population currently uses traditional herbal remedies as complementary or alternative medicine and 80% of the population in developing countries depends almost totally on them for their primary ...
J. Perrot +6 more
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Current perspectives in herbal and conventional drug interactions based on clinical manifestations
Future Journal of Pharmaceutical Sciences, 2021 Background Herbs are an important source of pharmaceuticals. Herbs are traditionally used by millions of peoples for medicine, food and drink in developed and developing nations considering that they are safe.
Ajaykumar Rikhabchand Surana +3 more
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Enzyme Activity of Natural Products on Cytochrome P450
Molecules, 2022 Drug-metabolizing enzymes, particularly the cytochrome P450 (CYP450) monooxygenases, play a pivotal role in pharmacokinetics. CYP450 enzymes can be affected by various xenobiotic substrates, which will eventually be responsible for most metabolism-based ...
Hua-Li Zuo +7 more
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Asian Journal of Medical Sciences, 2020 Background: Multidisciplinary therapy is gaining popularity and drug herb interactions is one of the biggest risk factor contributing to therapeutic failures or toxicities. Apart from analysis of one of such Drug-Herb combinations, this work also aims at
Lovelyn Joseph +2 more
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Everyday Evaluation of Herb/Dietary Supplement–Drug Interaction: A Pilot Study
Medicines, 2023 A lack of reliable information hinders the clinician evaluation of suspected herb–drug interactions. This pilot study was a survey-based study conceived as a descriptive analysis of real-life experiences with herb–drug interaction from the perspective of
Joao Victor Souza-Peres +5 more
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