Results 21 to 30 of about 48,877 (264)

Phytochemical Comparison of Medicinal Cannabis Extracts and Study of Their CYP-Mediated Interactions with Coumarinic Oral Anticoagulants

open access: yesMedical Cannabis and Cannabinoids, 2023
Introduction: Treatment with cannabis extracts for a variety of diseases has gained popularity. However, differences in herb-drug interaction potential of extracts from different plant sources are poorly understood.
Andrea Treyer   +4 more
doaj   +1 more source

Evaluation of potential drug- herb interactions among a group of Palestinian patients with chronic diseases [PDF]

open access: yes, 2015
BACKGROUND: The aim of this study was to find the prevalence of potential drug-herb interactions in patients with chronic diseases and identify factors associated with these interactions if present.
Ihab Shalalfeh   +6 more
core   +1 more source

Effects of Danshen tablets on pharmacokinetics of amlodipine in rats

open access: yesPharmaceutical Biology, 2019
Context: Danshen tablets (DST), an effective traditional Chinese multi-herbal formula, are often combined with amlodipine (ALDP) for treating coronary heart disease.
Haixia Zhang   +4 more
doaj   +1 more source

16S rRNA gene profiling and genome reconstruction reveal community metabolic interactions and prebiotic potential of medicinal herbs used in neurodegenerative disease and as nootropics. [PDF]

open access: yes, 2019
The prebiotic potential of nervine herbal medicines has been scarcely studied. We therefore used anaerobic human fecal cultivation to investigate whether medicinal herbs commonly used as treatment in neurological health and disease in Ayurveda and other ...
Albayrak, Levent   +10 more
core   +5 more sources

Effects of triptolide on pharmacokinetics of amlodipine in rats by using LC–MS/MS

open access: yesPharmaceutical Biology, 2018
Context: Triptolide and amlodipine are often simultaneously used for reducing urine protein excretion after renal transplantation in China clinics. Objective: This study investigated the effects of triptolide on the pharmacokinetics of amlodipine in male
Chengyin Zhang   +3 more
doaj   +1 more source

Characterization of anti-leukemia components from Indigo naturalis using comprehensive two-dimensional K562/cell membrane chromatography and in silico target identification. [PDF]

open access: yes, 2016
Traditional Chinese Medicine (TCM) has been developed for thousands of years and has formed an integrated theoretical system based on a large amount of clinical practice.
Cao, Yan   +9 more
core   +1 more source

Effects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism

open access: yesPharmaceutical Biology, 2018
Context: Ginkgo leaf tablets (GLTs) and losartan are often simultaneously used for the treatment of hypertension in Chinese clinics. However, the herb–drug interaction between GLT and losartan is still unknown.
Baiping Dong   +3 more
doaj   +1 more source

Identification of cytochrome P450 isoenzymes involved in the metabolism of 23-hydroxybetulinic acid in human liver microsomes

open access: yesPharmaceutical Biology, 2020
Context 23-Hydroxybetulinic acid (23-HBA), a major active constituent of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae), exhibits potential antitumor activity. Its metabolism, however, has not yet been studied.
Ying Zhou, Jinhua Wen, Guangji Wang
doaj   +1 more source

Evaluation of lentinan effects on cytochrome P450 activity in rats by a cocktail method [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): In this study, a cocktail of probe drugs was used to assess whether lentinan could influence the activities of rat enzymes CYP3A4, CYP2D6, CYP1A2, CYP2C19, and CYP2C9 in vivo.
Yiping Lin   +8 more
doaj   +1 more source

Drug-Drug Interaction Potential, Cytotoxicity, and Reactive Oxygen Species Production of Salix Cortex Extracts Using Human Hepatocyte-Like HepaRG Cells

open access: yesFrontiers in Pharmacology, 2021
Herbal preparations of willow bark (Salix cortex) are available in many countries as non-prescription medicines for pain and inflammation, and also as dietary supplements.
João Victor Dutra Gomes   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy