Results 61 to 70 of about 48,877 (264)

In vitro evaluation of the inhibition potential of echinacoside on human cytochrome P450 isozymes

BMC Complementary Medicine and Therapies, 2022
Background Echinacoside (ECH) possesses a wide range of biological activity. This present study analyzes the effect of ECH on cytochrome P450 isozymes (CYPs) activities of human liver microsomes.
Yujie Wu, Aiqing Qiao, Shu Lin, Lijia Chen   +3 more
doaj   +1 more source

Artemisinin: From Chinese Herbal Medicine to Modern Chemotherapy [PDF]

, 2019
Malaria is a disease that has blighted humankind since early times. The first antimalarial treatment available to Europeans was the dried bark of the cinchona tree from Peru. The main problem in its use was adulteration by other material.
Butler, Anthony
core   +1 more source

Pregnancy, prescription medicines and the potential risk of herb-drug interactions:a cross-sectional survey [PDF]

, 2017
Funding All funding was from institutional resource. JSM, AS are employed by the University of Aberdeen. DS is employed by the Robert Gordon University. BP and CR are employed by NHS Scotland.
A Fugh-Berman, A Lupattelli, A Smeriglio, A Steel, A Vickers, AA Izzo, AA Mitchell, Abdul R. Pallivalapila, AR Pallivalapila, AR Pallivalapilla, AR Pallivalapilla, Ashalatha Shetty, Binita Pande, CH Chuang, Craig Rore, DA Forster, DA Kennedy, Derek Stewart, E Ernst, F Facchinetti, GG Briggs, H Nordeng, H Nordeng, HG Hall, J Adams, J Boivin, J Henderson, James S. McLay, JJ Dugoua, JR Daw, K Moussally, K Moussally, KJ Hunt, KM Kuczkowski, L Cuzzolin, L Holst, M Elvin-Lewis, M Tabatabaee, MC Mothupi, ME Palmer, Moza Al Hail, Naila Izzati, O Stephansson, P Posadzki, RE Graham, RE Westfall, RJ Ko, S Eardley, TC Clarke, W Abebe   +49 more
core   +4 more sources

Effects of astragaloside IV on the pharmacokinetics of omeprazole in rats

Pharmaceutical Biology, 2019
Context: Omeprazole and astragaloside IV (AS-IV) are widely used for the treatment of gastric ulcers in China clinics. Objective: This study investigates the effects of AS-IV on the pharmacokinetics of omeprazole in rats.
Wei Liu, Guozhi Liu, Jing Liu
doaj   +1 more source

The effects of triptolide on the pharmacokinetics of sorafenib in rats and its potential mechanism

Pharmaceutical Biology, 2017
Context: Combining sorafenib with triptolide could inhibit tumour growth with greater efficacy than single-agent treatment. However, their herb–drug interaction remains unknown.
Xianming Wang, Xin Zhang, Fei Liu, Minghai Wang, Shiyong Qin   +4 more
doaj   +1 more source

High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care

Acta Pharmaceutica Sinica B, 2019
Managing the dysregulated host response to infection remains a major challenge in sepsis care. Chinese treatment guideline recommends adding XueBiJing, a five-herb medicine, to antibiotic-based sepsis care.
Jian Li, Olajide E. Olaleye, Xuan Yu, Weiwei Jia, Junling Yang, Chuang Lu, Songqiao Liu, Jingjing Yu, Xiaona Duan, Yaya Wang, Kai Dong, Rongrong He, Chen Cheng, Chuan Li   +13 more
doaj   +1 more source

Targeting apoptosis signaling in pancreatic cancer [PDF]

, 2011
The ability to escape apoptosis or programmed cell death is a hallmark of human cancers, for example pancreatic cancer. This can promote tumorigenesis, since too little cell death by apoptosis disturbs tissue homeostasis.
Fulda, Simone
core   +2 more sources

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

In vitro inhibitory effects of bergenin on human liver cytochrome P450 enzymes

Pharmaceutical Biology, 2018
Context: Bergenin, isolated from the herb of Bergenia purpurascens (Hook. f. et Thoms.) Engl., has anti-inflammatory, antitussive, and wound healing activities.
Gang Dong, Yun Zhou, Xiaoli Song
doaj   +1 more source