Artificial intelligence models Traditional Chinese Medicine principles to integrate with biomedicine
Using 26,339 model‐eligible Traditional Chinese Medicine (TCM) formula records, we trained an autoencoder following TCM's compression–expansion logic to learn the TCM embedding space (TCM‐ES), quantifying symptom‐pattern–formula mappings. TCM‐ES aligns with conventional TCM principles not used in training.
Haoran Li +12 more
wiley +1 more source
Herbal medicine for oral ulcer treatment: Mechanisms, efficacy, and therapeutic potential. [PDF]
Lin SZ +4 more
europepmc +1 more source
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley +1 more source
PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang +6 more
wiley +1 more source
Jing Si Herbal Tea Aqueous Extract Modulates G-CSF-Induced Hematopoietic Stem and Progenitor Cells Mobilization and Mitigates Associated Pain in a Murine Model. [PDF]
Lyu JY +8 more
europepmc +1 more source
Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
wiley +1 more source
Herbal or conventional medicine? A cross-sectional study of Jordanian university students' preferences for cold and flu treatment. [PDF]
Al-Magableh M +7 more
europepmc +1 more source
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley +1 more source
Clinical Evidence of Orally Administered Herbal Preparations for Supportive Cancer Care: A PRISMA Systematic Review of Randomized Clinical Trials (1990-2026). [PDF]
Moreno-Ponce R +14 more
europepmc +1 more source
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol +4 more
wiley +1 more source

