Results 101 to 110 of about 16,652 (272)

Family quality‐of‐life burden in chronic spontaneous urticaria: A multicentre study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Poor control of chronic spontaneous urticaria (CSU) significantly worsens family members' quality of life, especially in emotional, physical, and social domains. Higher disease severity was linked to increased caregiving burden and household expenditures, highlighting the need for family‐centred CSU care and support across diverse global populations ...
Beatrice Martinez Zugaib Abdalla, Roberta Fachini Jardim Criado, Kanokvalai Kulthanan, Emek Kocatürk, Ivan Cherrez‐Ojeda, Ana Maria Giménez‐Arnau, Marcus Maurer, Luis Felipe Ensina, Jonathan A. Bernstein, Michihiro Hide, Sergio Duarte Dortas Junior, Solange Oliveira Rodrigues Valle, Gabriela Dias, Paraskevi Xepapadak, Priyanshi Dangi, Indrashis Podder, Vesna Trajkova, Natasa Teovska Mitrevska, Iman Hamed Nasr, Bushra Al Hinai, Joanna Bartosińska, Dorota Krasowska, Paulina Szczepanik‐Kułak, Hilal Gungor, Deniz Ozceker, Kübra Çiçek, Esen Özkaya, Yasemin Erdem, Mücahit Ergün, Mustafa Tosun, Rabia Oztas Kara, Jie Li, Anastasia Allenova, Paulo Ricardo Criado   +33 more
wiley   +1 more source

Berotralstat for the prophylaxis of hereditary angioedema—Real‐world evidence data from the United Kingdom [PDF]

, 2023
Manisha Ahuja, Anthony D. Dorr, Eniola Bode, Anne Boulton, Matthew Buckland, Samuel Chee, Claire Dalley, Sarah Denman, Anjali Ekbote, Shuayb Elkhalifa, Tariq El‐Shanawany, Efrem Eren, Archana Herwadkar, Tomaz Garcez, Harichandana Ghanta, Alexandros Grammatikos, Sofia Grigoriadou, Rashmi Jain, Lorena Lorenzo, Ania Manson, Emily Moon, Sai Murng, Aveen Murphy, Leman Mutlu, Nicholas Peters, Kavitha Sooriyakumar, Catherine B. Stroud, Katie Townsend, Robert Yellon, Patrick Yong, Sorena Kiani‐Alikhan   +30 more
openalex   +1 more source

Multi‐omics profiling of chronic immune‐mediated skin diseases: SKINERGY protocol and strategic evaluation

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The SKINERGY study will investigate six immune‐mediated inflammatory skin diseases through a nationwide collaboration across all Dutch university medical centres. Involving 720 patients and 120 healthy volunteers, it is aimed at generating a high‐quality dataset to identify biomarkers that enable personalized treatment strategies and improved disease ...
N. G. Koster, J. M. P. A. van den Reek, E. M. G. J. de Jong, S. van Beugen, A. I. M. van Laarhoven, I. Haeck, M. de Bruin‐Weller, M. L. Schuttelaar, B. Horvath, A. Gostyński, A. Knulst, M. H. Vermeer, L. Nguyen, L. Gerbens, P. Spuls, M. A. Middelkamp‐Hup, V. Exadaktylos, T. Niemeyer‐van der Kolk, A. R. Schrader, A. M. Sluijmers, J. Versteeg, B. W. M. Arents, I. van Ee, J. L. A. G. van der Zon, M. de Leeuw, T. de Leeuw, P. van den Broek, C. Berkhof, D. Vellinga, S. Weidinger, S. Dubrac, Y. Li, M. van Steensel, M. Marchetti‐Deschmann, M. Maurer, H. van der Zee, J. Damman, D. J. Hijnen, F. Wijk, M. M. B. Seyger, H. Röckmann, D. M. W. Balak, M. B. A. van Doorn, R. Rissmann, The Next Generation ImmunoDermatology (NGID) consortium, Rob Vreeken, Eva Cuypers, Boudewijn Lelieveldt, Abdoel El Ghalbzouri, Hanna Niehues, Ellen van den Bogaard, Tom Ederveen, Els van der Pool, Nanda Olde, Debra Trampe, Ellen Stijl‐’t Hart, Lisanne Wezendonk, Johan Westerhuis, Huma Shehwana, Joerg Schreiber, Jeremy Bost, Mie Bech Lukassen, Jimmy Bakker, Juliette Simons, Fauve van den Berge, Colin Spence, Elise Beljaards, Anastasiia Myronenko, Mariona Oliver   +68 more
wiley   +1 more source

Hereditary angioedema: how to approach it at the emergency department?

Einstein (São Paulo)
Angioedema attacks are common causes of emergency care, and due to the potential for severity, it is important that professionals who work in these services know their causes and management.
Faradiba Sarquis Serpa, Eli Mansour, Marcelo Vivolo Aun, Pedro Giavina-Bianchi, Herberto José Chong Neto, Luisa Karla Arruda, Regis Albuquerque Campos, Antônio Abílio Motta, Eliana Toledo, Anete Sevciovic Grumach, Solange Oliveira Rodrigues Valle   +10 more
doaj   +2 more sources

Attempts to detect retrotransposition and de novo deletion of Alus and other dispersed repeats at specific loci in the human genome [PDF]

, 2001
Dispersed repeat elements contribute to genome instability by de novo insertion and unequal recombination between repeats. To study the dynamics of these processes, we have developed single DNA molecule approaches to detect de novo insertions at a single
AJ Jeffreys, AJ Jeffreys, AR Jeffs, BF Koop, D Stoppa-Lyonnet, F Rouyer, HH Kazazian, HH: Kazazian, J Murray, J: Jurka, M: Kimura, PE Carter, PL Deininger, Y Miki, Z Wong   +14 more
core   +1 more source

Managing Primary Immunodeficiency Immunoglobulin Replacement Therapy‐Related Adverse Events With Recombinant Human C1 Esterase Inhibitor Prophylaxis: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Immunoglobulin replacement therapy (IRT) for primary immunodeficiency reduces infection risk and subsequent complications and can be lifesaving. However, IRT can cause severe systemic adverse events (AEs) that may limit adequate dosing. These AEs may be caused, in part, by activation and/or consumption of complement proteins, thereby lowering ...
Douglas H. Jones, Heidi Memmott
wiley   +1 more source

Angioedema

Allergy, Asthma & Clinical Immunology
Angioedema can occur in the absence of urticaria and can be broadly divided into three main categories: mast cell-mediated (e.g., histamine), non-mast-cell-mediated (bradykinin-induced) and idiopathic angioedema.
Gina Lacuesta, Stephen D. Betschel, Ellie Tsai, Harold Kim   +3 more
doaj   +1 more source

Successful anesthetic management during abdominal wall-lifting laparoscopic cholecystectomy in a patient with hereditary angioedema

JA Clinical Reports, 2018
Background Hereditary angioedema is a rare genetic disorder resulting from an inherited deficiency or dysfunction of the C1-esterase inhibitor. In the anesthetic management of such patients, special caution should be exercised while attempting tracheal ...
Masashi Fujii, Takayuki Higashiguchi, Nobuaki Shime, Yasuyo Kawabata   +3 more
doaj   +1 more source

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak, Daniella Magen, Karin Weiss, Tamar Paperna, Suhair Hanna, Amos Etzioni, Adi Miller‐Barmak, Yonatan Butbul Aviel   +7 more
wiley   +1 more source

Elevated level of circulating VEGF in Chinese patients with hereditary angioedema and its correlation with disease status

Orphanet Journal of Rare Diseases
Background Hereditary angioedema (HAE) is a rare inherited disease characterized by recurrent, potentially life-threatening angioedema. The vascular endothelium dysfunction is reported to play a role in angioedema episodes.
Ruoyu Ji, Yijing Xu, Yuxiang Zhi
doaj   +1 more source