Results 201 to 210 of about 305,201 (264)

Prevalence of Constitutional Pathogenic Variant in a Cohort of 348 Patients With Multiple Primary Cancer Addressed in Oncogenetic Consultation. [PDF]

Mol Genet Genomic Med
Lepage M, Uhrhammer N, Molnar I, Privat M, Ponelle-Chachuat F, Gay-Bellile M, Bidet Y, Cavaillé M.   +7 more
europepmc   +1 more source

Combined Hepatic and Portal Vein Thrombosis due to Uncommon Hereditary Factors for Thrombophilia in Young Adult

, 2017
Afaf Hemeda
openalex   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Genetic Features of Tumours Arising in the Context of Suspected Hereditary Cancer Syndromes with <i>RAD50</i>, <i>RAD51C/D</i>, and <i>BRIP1</i> Germline Mutations, Results of NGS-Reanalysis of BRCA/MMR-Negative Families. [PDF]

Genes (Basel)
Arranz-Ledo M, Infante M, Lastra E, Olaverri A, Orozco M, Mateo LC, Martínez N, Hernández L, Durán M.   +8 more
europepmc   +1 more source

Peer review report 1 on “Hereditary factors are unlikely behind unusual pattern of early - onset colorectal cancer in Egyptians a study of family history and pathology features in Egyptians with large bowel cancer (cross-sectional study)”

, 2017

openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Prediction of hereditary angioedema during attacks in patients with recurrent angioedema: Awareness at a glance with the hereditary angioedema prediction score. [PDF]

Clin Transl Allergy
Demir S, Olgaç M, Yeğit OO, Toprak İD, Çakmak ME, Hormet Mİ, Öztop N, Korkmaz P, Çelik ŞK, Karabacak DE, Kahveci N, İmren IG, Erden B, Coşkun R, Karadağ P, Ünal D, Gelincik A.   +16 more
europepmc   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Isolated and Syndromic Genetic Optic Neuropathies: A Review of Genetic and Phenotypic Heterogeneity. [PDF]

Int J Mol Sci
Zeppieri M, Gagliano C, Di Maita M, Avitabile A, Gagliano G, Dammino E, Tognetto D, Cordeiro MF, D'Esposito F.   +8 more
europepmc   +1 more source