Results 201 to 210 of about 427,242 (236)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Discovering, Integrating, and Reinterpreting the Molecular Logic of Life: From Classical Theories of Heredity to an Extended Functional Perspective on the Central Dogma. [PDF]

Life (Basel)
Grădinaru AC.
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Tips of family history taking in diagnosing Alport syndrome: a report of six cases. [PDF]

CEN Case Rep
Mori T.
europepmc   +1 more source

AI-driven patient-centered care: A digital transformation framework for gynecologic cancer genetic counseling. [PDF]

Sci Prog
Yang R, Zheng X, Deng Y, Deng M, Jiang J, Miao J.   +5 more
europepmc   +1 more source

Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors

, 2012
Håkan Lövkvist
openalex   +1 more source

Risk and Outcomes of Secondary Cancer Among Lung Cancer Survivors After Definitive Treatment.

JAMA Netw Open
McMillan MT, Yariv O, Raoof S, Chaft JE, Park BJ, Jones DR, Shaverdian N, Ruggiero J, Jackson U, Li BT, Iyengar P, Gomez DR.   +11 more
europepmc   +1 more source

Early-Onset Fibrocalculous Pancreatic Diabetes Associated With SPINK1 Variants In Trans: A Rare Genetic Case. [PDF]

Diabetes Care
Kostrzewska P, Kuca P, Łaz R, Maksymiuk-Kłos A, Witek P.   +4 more
europepmc   +1 more source

Hereditary Hyperferritinemia-Cataract Syndrome: A Pediatric Case Without Congenital Cataract. [PDF]

Cureus
Hemanna A, Sidlow R.
europepmc   +1 more source