Results 101 to 110 of about 15,219 (276)

Sporadic Porphyria Cutanea Tarda, Cutaneous Sarcoidosis, and Compound Heterozygosity of HFE Mutations Cys282Tyr and His63Asp—A Case Report

eJHaem, Volume 6, Issue 3, June 2025.
ABSTRACT Porphyria cutanea tarda (PCT) is caused by inherited or acquired defects of uroporphyrinogen decarboxylase (UROD) in the heme biosynthetic pathway. Altered iron homeostasis via hemochromatosis gene (HFE) mutations is one of many susceptibility factors associated with the sporadic form of PCT.
Jowon L. Kim, Richard Crawford, Ian Marie Lano, Hayley Merkeley   +3 more
wiley   +1 more source

On strongly quasi-hereditary algebras [PDF]

arXiv, 2016
Let $A$ be a finite dimensional algebra over an algebraically closed field $\mathbf{k}$. If $A$ is quasi-hereditary and the projective dimensions of all standard modules are at most one, then $A$ is called left strongly quasi-hereditary. In this paper, we construct a special heredity chain for left strongly quasi-hereditary algebras.
arxiv  

Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study. [PDF]

, 2011
Because body iron burden is inversely associated with lead absorption, genes associated with hemochromatosis may modify body lead burden. Our objective was to determine whether the C282Y and/or H63D hemochromatosis gene (HFE) is associated with body lead
Aro, Antonio, Hu, Howard, Schwartz, Joel David, Senter, Jody, Silverman, Edwin Kepner, Sparrow, David, Tsaih, Shring-Wern, Weiss, Scott Tillman, Wright, Robert O.   +8 more
core   +1 more source

Critical Role of Skin in Pathogenesis: Bidirectional Crosstalk Between Skin and Multiple Organs

MedComm – Future Medicine, Volume 4, Issue 2, June 2025.
The skin functions as both a protective barrier and an autonomous immune organ, maintaining dynamic interactions with internal organs. This review analyzes skin‐organ crosstalk mechanisms, highlighting key cytokines (particularly IL‐17A) and microbial metabolites that mediate interorgan communication.
Wende Deng, Junyi Liu, Changheng Tang, Zhenghao Li, Ying Qiu, Han Zhou, Lanxuan Yang, Ting Li   +7 more
wiley   +1 more source

Mutation Analysis in Hereditary Hemochromatosis

Blood Cells, Molecules, and Diseases, 1996
The DNA of 147 patients of European origin clinically diagnosed with idiopathic hemochromatosis and 193 controls was examined for mutations of the HLA-H gene at nt 845 and nt 187. One hundred twenty-one (82.3%) of the hemochromatosis patients were homozygous and 10 (6.8%) heterozygous for the 845A (C282Y) mutation.
Michele Adams, Michael P. Kosty, Amy E. Ten Elshof, Charles P. Venditti, Charles P. Venditti, Carol West, Glenn S. Gerhard, Pauline Lee, Pradyumna D. Phatak, Terri Gelbart, Ryan Blackstone, Ernest Beutler, Karen Chorney, Michael J. Chorney, Paul J. Pockros, Nicole K. Seese   +15 more
openaire   +3 more sources

Do All Hemochromatosis Patients Have the Same Origin? A Pilot Study of Mitochondrial DNA and Y-DNA

Canadian Journal of Gastroenterology, 2011
BACKGROUND: Mitochondrial DNA (mtDNA) and Y-DNA analysis have been widely used to predict ancestral origin. Genetic anthropologists predict that human civilizations may have originated in central Africa one to two million years previously.
Caitlin J Symonette, Paul C Adams
doaj   +1 more source

Genotypic and phenotypic spectra of hemojuvelin mutations in primary hemochromatosis patients: a systematic review

Orphanet Journal of Rare Diseases, 2019
Hereditary hemochromatosis (HH) is a genetic disorder that causes excess absorption of iron and can lead to a variety of complications including liver cirrhosis, arthritis, abnormal skin pigmentation, cardiomyopathy, hypogonadism, and diabetes ...
Xiaomu Kong, Lingding Xie, Haiqing Zhu, Lulu Song, Xiaoyan Xing, Wenying Yang, Xiaoping Chen   +6 more
doaj   +1 more source

Hereditary Discrepancies in Different Numbers of Colors II [PDF]

arXiv, 2006
We bound the hereditary discrepancy of a hypergraph $\HH$ in two colors in terms of its hereditary discrepancy in $c$ colors. We show that $\herdisc(\HH,2) \le K c \herdisc(\HH,c)$, where $K$ is some absolute constant. This bound is sharp.
arxiv  

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, Volume 45, Issue 3, Page 177-201, June 2025.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source

Recollements of abelian categories and ideals in heredity chains - a recursive approach to quasi-hereditary algebras [PDF]

arXiv, 2018
Recollements of abelian categories are used as a basis of a homological and recursive approach to quasi-hereditary algebras. This yields a homological proof of Dlab and Ringel's characterisation of idempotent ideals occuring in heredity chains, which in turn characterises quasi-hereditary algebras recursively.
arxiv