Results 211 to 220 of about 28,801 (226)

Psychotropic drugs, HERG, and the heart

The Lancet, 2000
J C, Hancox, H J, Witchel
openaire   +2 more sources

Computational investigations of hERG channel blockers: New insights and current predictive models

Advanced Drug Delivery Reviews, 2015
Bruno O Villoutreix, Olivier Taboureau
exaly  

A quantitative assessment of hERG liability as a function of lipophilicity

Bioorganic and Medicinal Chemistry Letters, 2007
Michael J Waring
exaly  

Reciprocal Control of hERG Stability by Hsp70 and Hsc70 With Implication for Restoration of LQT2 Mutant Stability

Circulation Research, 2011
Peili Li, Masaru Kato, Junichiro Miake   +2 more
exaly  

hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms

Heart Rhythm, 2016
Donald D Chang, R Suzanne Zukin, Henry M Colecraft   +2 more
exaly  

Arsenic trioxide-induced hERG K+ channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression

Biochemical Pharmacology, 2013
Zengxiang Dong, Kaiping Zhang, Yan Gong   +2 more
exaly  

HERG‐channels

2008
openaire   +1 more source

EXPANDING THE SCOPE OF THE hERG BINDING ASSAY: hERG TRAFFICKING AND METABOLITE TESTING

Journal of Pharmacological and Toxicological Methods, 2007
Colleen Doherty, Arek Raczynski, Hong Zang, Suresh Balani, Scott Coleman, Carl Alden, Peter Smith, Vivek J. Kadambi   +7 more
openaire   +1 more source

Mechanism of Block and Identification of the Verapamil Binding Domain to HERG Potassium Channels

Circulation Research, 1999
exaly  

HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium

British Journal of Cancer, 2000
Annarosa Arcangeli
exaly