Results 111 to 120 of about 48,510 (233)

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 869-878, March 2026.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

Exendin-4 enhances GLP-1 signaling and reduces anxiety-like behaviors in male heroin withdrawal mice. [PDF]

open access: yesPLoS One
Xiang Y   +9 more
europepmc   +1 more source

Olanzapine Attenuates the Morphine‐Induced Conditioned Place Preference: The Involvement of the D2‐Like Dopamine Receptors

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
The results of this study demonstrated that olanzapine can inhibit morphine‐induced CPP behavior during the acquisition, expression, and extinction phases. These effects are likely mediated by the inhibition of dopamine receptors and a reduction in D2R protein expression in the HIP.
Farkhondeh Rzazzaghi‐ Firozjaei   +6 more
wiley   +1 more source

The Mediating Role of Emotion Dysregulation in the Association Between Impulsivity and Severity of Substance Dependence

open access: yesClinical Psychology &Psychotherapy, Volume 33, Issue 2, March/April 2026.
ABSTRACT Substance use disorders (SUDs) are among the leading causes of morbidity and mortality globally. Identification of aetiological factors related to the severity of substance use can offer targets for therapeutic interventions. Role of impulsivity and emotion dysregulation in SUDs is well established.
Giovanni Mansueto   +4 more
wiley   +1 more source

Phenomenological research in the field of Infant Mental Health and Early Childhood (IECMH) ‐A mapping review

open access: yesInfant Mental Health Journal: Infancy and Early Childhood, Volume 47, Issue 2, March 2026.
Abstract Infant Mental Health and Early Childhood (IECMH) is a field of study of infants and the developing relationship and the optimal development between infants and their caregivers. Phenomenological research within the well‐being of infants and caregivers has core importance in the comprehension of the subjectivity of the infant and the attachment
Minna Sorsa, Bente Dahl, Idun Røseth
wiley   +1 more source

Proteomic Insights into Heroin Use: Links to Neurodegeneration. [PDF]

open access: yesMol Neurobiol
Sürmen MG   +6 more
europepmc   +1 more source

MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential

open access: yesMedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman   +7 more
wiley   +1 more source

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