Results 91 to 100 of about 72,393 (263)

Thiol/disulphide homeostasis in men with heroin addiction [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2014
Objective: Heroin addicts have increased oxidative stress which can disturb thiol/disulfide (SH/SS) homeostasis, causing disulfide formation. No study has determined the serum thiol amount and blood disulfide amount in heroin addicts.
vahap ozan kotan, fatma meric yilmaz, salim neselioglu, ozcan erel, ihsan tuncer okay, serkan kiral, abdurrahim bakirhan, erol goka   +7 more
doaj  

[News Clip: Heroin]

, 1958
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about Mack Finis Thomas, Jr. being questioned in Dallas following his early morning arrest as he tried to sell two ounces of heroin to a detective posing as an ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis

Addiction, EarlyView.
Abstract Background and aims In British Columbia, Canada, an initiative was implemented in 2020 to reduce overdose mortality by prescribing pharmaceutical opioids (primarily hydromorphone) as a substitute for the toxic unregulated drug supply. This study estimated changes in the level and trend of unregulated opioid use and non‐prescribed hydromorphone
Erica McAdam, Mohammad Karamouzian, Michael John Milloy, Carmen Verdicchio, Eric C. Sayre, Kanna Hayashi, Thomas Kerr, Kora DeBeck   +7 more
wiley   +1 more source

Gray matter density negatively correlates with duration of heroin use in young lifetime heroin-dependent individuals

, 2009
Numerous studies have documented cognitive impairments and hypoactivity in the prefrontal and anterior cingulate cortices in drug users. However, the relationships between opiate dependence and brain structure changes in heroin users are largely unknown.
Zhu, Zude, Lee, Tatia M. C., Tatia M.C. Lee, Yuan, Yi, Zou, Zhiling, Weng, Xuchu, Liu, Yijun, Yuan, Fei, Shi, Jinfu   +8 more
core   +1 more source

Neuroinflammatory history results in overlapping transcriptional signatures with heroin exposure in the nucleus accumbens and alters responsiveness to heroin in male rats

Translational Psychiatry
Recent progress in psychiatric research has highlighted neuroinflammation in the pathophysiology of opioid use disorder (OUD), suggesting that heightened immune responses in the brain may exacerbate opioid-related mechanisms.
Gabriele Floris, Mary Tresa Zanda, Konrad R. Dabrowski, Stephanie E. Daws   +3 more
doaj   +1 more source

Prescribed alternative stimulants among people who use unregulated stimulants: Examining the association between maximum dose reached and medication discontinuation in the first 3 years of implementation in British Columbia, Canada

Addiction, EarlyView.
Abstract Background and aims In 2020, British Columbia (BC), Canada, introduced ‘Prescribed Alternatives’ (PA) as an approach to offering regulated substances to people accessing the unregulated supply. This study aimed to estimate and compare prescribing characteristics of dextroamphetamine and methylphenidate stimulant PAs in BC, to estimate ...
Bin Zhao, Kevin Hu, Roshni Desai, Shania Au, Kali‐olt Sedgemore, Vitor Tardelli, Addie Carter, Paxton Bach, Christian Schutz, Amanda Slaunwhite, Alexis Crabtree, Heather Palis   +11 more
wiley   +1 more source

Forging a Path for Abstinence from Heroin: A grounded theory of detoxification-seeking

Grounded Theory Review: An International Journal, 2011
Through a classic grounded theory approach, this study conceptualises that the main concern of heroin users who are seeking detoxification is giving up heroin use; ‘getting clean.’Forging a path for abstinence explains how people respond to their concern
Marie Claire Van Hout, BSc.,MSc., PhD., Anne McDonnell, BA, HDip.   +1 more
doaj  

Drug use disorders among people convicted of large‐, moderate‐ and small‐scale drug supply crimes: A register‐based retrospective comparative study

Addiction, EarlyView.
Abstract Background and aims Heavy drug use has been associated with small‐scale drug crime, but the substance use histories of individuals involved in the manufacturing, smuggling and wholesaling of larger quantities of drugs [here referred to as serious drug crimes (SDC)] have been largely unexamined.
Julie Elizabeth Brummer, Freja Ilsing Magnussen, Morten Hesse, Thomas Friis Søgaard   +3 more
wiley   +1 more source

The association between chronic pain and non‐fatal overdose in people who inject drugs: Longitudinal cohort study in Montreal, Canada, 2017 to 2025

Addiction, EarlyView.
Abstract Background and aims The prevalence of chronic pain is elevated among people who inject drugs. Chronic pain may motivate drug use, potentially increasing the risk of non‐fatal overdose. We aimed to estimate the association between chronic pain and non‐fatal overdose in people who inject drugs.
Sarah Larney, Geng Zang, Harika Dasari, M. Gabrielle Pagé, Farzaneh Vakili, Adelina Artenie, Valérie Martel‐Laferrière, Nanor Minoyan, Sasha Udhesister, Julie Bruneau   +9 more
wiley   +1 more source

Study of the Transition from Non-Injection to Injection in Heroin Users

پزشکی بالینی ابن سینا, 2010
Introduction & Objectives: The goal of our study was to elucidate the time and factors influencing the transition from non-injection to injection among male heroin users.
Mosaieb Yarmohammadi Vasel, Fatemeh Ghanadi   +1 more
doaj