Results 81 to 90 of about 72,393 (263)

Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]

open access: yes, 1998
The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Krappel, C.   +9 more
core   +1 more source

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson   +13 more
wiley   +1 more source

The Effects of Cocaine and Heroin Prices on Drug-Related Emergency Department Visits [PDF]

open access: yes
This paper estimates the empirical relationship between the prices of cocaine and heroin and objective indicators of use. The set of outcomes is drug related hospital emergency department admissions where cocaine and heroin are cited, for 21 large U.S ...
Dhaval Dave
core  

Craving and personal functioning as mediators of extended‐release buprenorphine efficacy: A four‐way decomposition analysis from a randomised trial

open access: yesAddiction, EarlyView.
Abstract Aims To investigate whether the treatment effect of extended‐release buprenorphine (BUP‐XR) on opioid‐free days in opioid use disorder (OUD) is mediated by reductions in opioid craving and improvements in personal functioning. Design and setting Exploratory causal mediation analysis using VanderWeele's four‐way decomposition framework in a 24 ...
John Marsden   +11 more
wiley   +1 more source

Injecting risk behaviours, self-reported mental health and crime [PDF]

open access: yes, 2013
This paper explores differences between two types of illicit drug users (heroin users and non-heroin users) in relation to injecting risk behaviours, self-reported mental health, driving and crime.Key findingsParticipants were divided into two groups ...
Jennifer Stafford, Lucy Burns
core  

Overdose reversal through peer intervention: Findings from the naloxone prospective outcome research study (NalPORS) on the effectiveness of overdose response by people who use opioids in the United Kingdom and Sweden

open access: yesAddiction, EarlyView.
Abstract Background/aims Take‐home naloxone (THN) programmes have been introduced in many European countries to provide non‐medically trained people who are likely to witness an opioid overdose, including people who use opioids, with a naloxone kit and training.
Nicola Metrebian   +31 more
wiley   +1 more source

The impact of harm reduction interventions on injection‐related bacterial infections among people who inject drugs: A systematic review

open access: yesAddiction, EarlyView.
Abstract Background and aims Injection‐related bacterial infections represent a major but under‐recognised health issue among people who inject drugs (PWID). Harm reduction interventions (HRIs) like needle and syringe programmes (NSP) and opioid agonist treatment (OAT) could mitigate their burden.
Anthony Cousien   +7 more
wiley   +1 more source

Supply-side reduction policy and drug-related harm [PDF]

open access: yes, 2014
Large-scale seizures of cocaine, heroin and amphetamine-type substances (ATS) do not result in any reduction in overdoses on these drugs or on arrests for use and possession of these drugs, according to this report.
Grant Sara   +4 more
core  

Health service utilization of heroin abusers: A retrospective cohort study

open access: yes, 2017
Aims: This study aimed to determine the patterns of medical service utilization among heroin users and to identify the factors associated with the frequency of utilization.
Chen, I-Ming;Huang, Charles Lung-Cheng;Yeh, Bao-Juan;Chien, Yi-Ling   +1 more
core   +1 more source

People experiencing homelessness and their experiences with substance use services for alcohol treatment in England: Journey mapping based on semi‐structured interviews

open access: yesAddiction, EarlyView.
Abstract Background and aims Alcohol consumption at high levels is common among people experiencing homelessness and contributes to inequalities. In relative terms these individuals are underrepresented in substance use services. This study captured common trajectories and identified barriers and facilitators to accessing treatment among a group of ...
Vera Helen Buss   +6 more
wiley   +1 more source

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