Results 121 to 130 of about 179,765 (329)

Troriluzole attenuates opioid intake, reinforcing efficacy, seeking behaviours, physical dependence and antinociceptive tolerance in rats

British Journal of Pharmacology, EarlyView.
Background and Purpose Riluzole, approved for amyotrophic lateral sclerosis (ALS), has a glutamate‐modulating profile favourable for mitigating opioid addiction. It reduces neuronal glutamate release and enhances glutamate reuptake, offering advantages over agents that only increase glutamate reuptake.
Ewa Galaj, Saadet Inan, Guo‐Hua Bi, Sonita Wiah, George Adamson, Allen B. Reitz, Zheng‐Xiong Xi, Scott M. Rawls   +7 more
wiley   +1 more source

Forging a Path for Abstinence from Heroin: A grounded theory of detoxification-seeking

Grounded Theory Review: An International Journal, 2011
Through a classic grounded theory approach, this study conceptualises that the main concern of heroin users who are seeking detoxification is giving up heroin use; ‘getting clean.’Forging a path for abstinence explains how people respond to their concern
Marie Claire Van Hout, BSc.,MSc., PhD., Anne McDonnell, BA, HDip.   +1 more
doaj  

Neuroinflammatory history results in overlapping transcriptional signatures with heroin exposure in the nucleus accumbens and alters responsiveness to heroin in male rats

Translational Psychiatry
Recent progress in psychiatric research has highlighted neuroinflammation in the pathophysiology of opioid use disorder (OUD), suggesting that heightened immune responses in the brain may exacerbate opioid-related mechanisms.
Gabriele Floris, Mary Tresa Zanda, Konrad R. Dabrowski, Stephanie E. Daws   +3 more
doaj   +1 more source

From the Mountaintops: What the World Can Learn from Drug Policy Change in Switzerland [PDF]

, 2010
Reviews Switzerland's drug policy of policing, prevention, treatment, and harm reduction, including low-threshold methadone programs, needle exchanges, and safe injection rooms.
Csete, Joanne
core  

Perceived Barriers and Potential Strategies for People Who Use Drugs in Accessing Oral Healthcare: A Qualitative Study of Service Providers

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objective Access to appropriate oral healthcare is vital for overall health and well‐being. However, people who use drugs (PWUD) often face significant barriers in accessing oral healthcare services. This qualitative study focused on exploring the perspectives of public oral health service providers and harm reduction workers to understand the
Tejashree Kangutkar, Mark Gussy, Ronald Knevel, Hanny Calache   +3 more
wiley   +1 more source

Morbidity and mortality from heroin dependence. 3. Relation of hepatitis to self-injection techniques. [PDF]

, 1968
T. H. Bewley, O. Ben-Arie, V. Marks
openalex   +1 more source

Making Accurate Judgements in Child Welfare: Comparing ChatGPT With Qualified Social Workers

Child &Family Social Work, EarlyView.
ABSTRACT This study compares the judgemental accuracy of child and family social workers (n = 581) with ChatGPT, a generative AI model. Using 12 anonymized referrals, participants were asked predictive questions to evaluate accuracy through Brier scores. ChatGPT outperformed the average social worker on 11 of the 12 referrals, though the difference was
David Wilkins, Verity Benett
wiley   +1 more source

Study of the Transition from Non-Injection to Injection in Heroin Users

پزشکی بالینی ابن سینا, 2010
Introduction & Objectives: The goal of our study was to elucidate the time and factors influencing the transition from non-injection to injection among male heroin users.
Mosaieb Yarmohammadi Vasel, Fatemeh Ghanadi   +1 more
doaj  

Morbidity and mortality from heroin dependence. 1. Survey of heroin addicts known to home office. [PDF]

, 1968
T. H. Bewley, O. Ben-Arie, I. Pierce James   +2 more
openalex   +1 more source

Heroin addiction in the United Kingdom (1954-1964). [PDF]

, 1965
T. H. Bewley
openalex   +1 more source