Results 141 to 150 of about 72,393 (263)

Evaluating Harm Reduction Advice From Large Language Models

Drug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction Large language models (LLM) and generative Artificial Intelligence are increasingly providing health information. We have applied a novel method to evaluate the harm reduction information generated by popular LLMs. We focused on the filtration of oral medications for injection and the availability of local harm reduction services.
Khy Choo, Nathan Smith, Bernadette Ward, Robert M. Lundin   +3 more
wiley   +1 more source

Understanding Consumption of Illicit Drugs and New Psychoactive Substances in Australia by Triangulating Drug Checking and Wastewater‐Based Epidemiology

Drug Testing and Analysis, Volume 18, Issue 10, Page 1244-1255, October 2026.
First Australian study combining wastewater‐based epidemiology and drug checking, demonstrating how complementary data sources enhance monitoring of illicit drugs and emerging psychoactive substances during high‐use periods. ABSTRACT Consumption of psychotropic drugs is a major economic and public health challenge in Australia.
Muhammad Usman, Malcolm McLeod, Dhayaalini Nadarajan, Joseph Clokey, Pritesh Prasad, Rory Verhagen, Benjamin Tscharke, Maurizio Quinto, Richard Bade   +8 more
wiley   +1 more source

Pharmacological Management of Opioid Use Disorder: A Systematic Review and Network Meta-Analysis: Prise en charge pharmacologique du trouble de l'usage des opiacés : revue systématique et méta-analyse en réseau. [PDF]

Can J Psychiatry
Rodrigues M, Dennis BB, Sadeghirad B, Oprea A, Malik M, Naji LN, McEvoy A, Malhotra D, Parpia S, Thabane L, Samaan Z.   +10 more
europepmc   +1 more source

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

Drug Testing and Analysis, Volume 18, Issue 10, Page 1296-1310, October 2026.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza, Náthaly C. B. F. Santos, Rafael Lanaro, Sara E. Walton, Alex J. Krotulski, Barry K. Logan, Mauricio Yonamine, Jose Luiz Costa   +7 more
wiley   +1 more source

GPCR Precision in Addiction Also Requires Ligand, Exposure, and Phenotype Precision. [PDF]

Drug Dev Res
Chen HH, Wei LC.
europepmc   +1 more source

Impacts of a Statewide Prescription Drug Monitoring Program—Healthcare Practitioner Perspectives

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT This study examined the perceived impacts of New South Wales' (NSW) statewide prescription drug monitoring program (PDMP; “SafeScript NSW”) from the perspective of prescribers and pharmacists, using a qualitative descriptive design. Fourteen prescribers and pharmacists who were users of NSW's PDMP completed semi‐structured interviews between ...
Emma Tay, Meredith Makeham, Tracey‐Lea Laba, Melissa Baysari   +3 more
wiley   +1 more source

Urinary antimony as a biomarker for differentiating heroin and Brown mixture use. [PDF]

J Food Drug Anal
Tsai SM, Hsiao YH, Chang YZ, Ho SW.
europepmc   +1 more source

“‘There’s no heroin here, it’s only a Dublin thing’ – it’s complete lies”.

, 2015
An Irish play tackles drug use head on. When she was just nine years old, Grace Dyas found a syringe in her garden. That experience led her to travelling the country in her early twenties to find out more about addiction, which culminated in the ...
Barry, Aoife
core  

Barriers and facilitators to detoxification from opioid substitution treatment: A mixed‐methods systematic review

Addiction, Volume 121, Issue 10, Page 2607-2619, October 2026.
Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw, Suleyman Shah, India Olchefske, Louise M. Paterson, Mike J. Crawford, Anne Lingford‐Hughes   +5 more
wiley   +1 more source

Understanding negative feedback and classical conditioning of autonomic responses in physiological regulation. [PDF]

Front Physiol
Ramsay DS, Woods SC.
europepmc   +1 more source