Results 81 to 90 of about 100,982 (338)
Naloxone dosing in the era of synthetic opioids: Applying the Goldilocks principle
Abstract The opioid overdose epidemic remains a critical public health crisis. In recent years, synthetic opioids like fentanyl and nitazenes, have driven a sharp rise in deaths. Naloxone, an opioid receptor antagonist, has been established as a key intervention for reversing opioid overdoses and saving lives.
Mariana Gonzalez Utrilla+8 more
wiley +1 more source
Background Blowfly larvae and pupae collected during post-mortem forensic investigation can be analysed to detect drugs or toxins in a dead body. Drug or toxin-contaminated tissues of human remains consumed by blowfly larvae are stored in the crop even ...
Nooratiny Ishak+3 more
doaj +1 more source
Abstract Background and Aims The subjective experience of drug craving is characterized by an overwhelming urge to consume substances. Due to strong validity and ease of use, self‐report measures are widely employed to assess substance‐related motivational dynamics.
Matin Toulami+9 more
wiley +1 more source
Abstract Aims To report the symptoms and aetiology of ketamine use disorder (KUD), gauge the effectiveness of current treatment services and identify strategies to enhance patient access and outcomes. Design Mixed‐methods, cross‐sectional questionnaire. Electronic survey from November 2023 to April 2024.
Rebecca E. Harding+7 more
wiley +1 more source
An age–period–cohort–interaction analysis of meth/amphetamine‐related deaths in Australia, 2001–2020
Abstract Background and Aims The number of meth/amphetamine related deaths in Australia has quadrupled in the last 20 years, primarily due to drug toxicity and suicide among individuals in their 30s and 40s. Previous analysis of Australian meth/amphetamine‐related deaths covered limited timeframes and causes, and there has been no exploration of the ...
Oisin Stronach+3 more
wiley +1 more source
Enhanced heroin self-administration and distinct dopamine adaptations in female rats
Brianna E. George+6 more
semanticscholar +1 more source
Abstract Background and aims An investigation of 24 weeks of extended‐release buprenorphine (BUP‐XR; Sublocade®) treatment for adults with opioid use disorder (OUD). Study aims were to characterise variations in clinical response, investigate personal factors influencing BUP‐XR experience and identify opportunities to tailor treatment interventions ...
Natalie Lowry+13 more
wiley +1 more source
Synthetic cannabinoids in e‐cigarettes seized from English schools
Abstract Background and aims People who use synthetic cannabinoids (SCs) report debilitating side effects and withdrawal symptoms, coupled with dependence. In the UK, SC use was believed to be largely restricted to prison, where they are the most common drug and associated with nearly half of non‐natural deaths, or poly‐drug users in the community who ...
Gyles E. Cozier+17 more
wiley +1 more source
A Contribution to the Therapeutic Action of Heroin [PDF]
BERNARD LAZARUS
openalex +1 more source