Results 51 to 60 of about 375,473 (301)
Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in
Fatemeh Mahmoudi+3 more
doaj
It has been proposed that genetic factors account for 30%–50% of the risk for cocaine and heroin addiction. The present study was aimed to find out the impact of µ-opioid receptor gene (OPRM1) rs1799971 A > G and rs9479757 polymorphisms on heroin ...
Mansour Shakiba+6 more
doaj +1 more source
The OxyContin Reformulation Revisited: New Evidence From Improved Definitions of Markets and Substitutes [PDF]
The opioid epidemic began with prescription pain relievers. In 2010 Purdue Pharma reformulated OxyContin to make it more difficult to abuse. OxyContin misuse fell dramatically, and concurrently heroin deaths began to rise. Previous research overlooked generic oxycodone and argued that the reformulation induced OxyContin users to switch directly to ...
arxiv
Narcotics Anonymous members in recovery from methamphetamine use disorder
Abstract Background and Objectives Methamphetamine use disorder (MUD) is a major public health problem, but there are no evidence‐based, best‐practice, pharmacologic, or behavioral treatments for it. Narcotics Anonymous (NA) may provide an option for referral for such patients.
Marc Galanter+2 more
wiley +1 more source
Aims: The primary aim of the current study was to assess the sexual history and behavior among treatment-naïve male patients of heroin dependence presenting to outpatient services; their knowledge and attitude about high-risk sexual behavior; and their ...
Nishtha Chawla+3 more
doaj +1 more source
Heroin addiction hijacks the Nucleus Accumbens: craving and reactivity to naturalistic stimuli [PDF]
Drug-related cues hijack attention away from alternative reinforcers in drug addiction, inducing craving and motivating drug-seeking. However, the neural correlates underlying this biased processing, its expression in the real-world, and its relationship to cue-induced craving are not fully established, especially in opioid addiction.
arxiv
Background: Substance dependence is well recognized as a complex biopsychosocial phenomenon. Complications arising out of it not only impairs life of substance-dependent patient but also causes enormous burden on their caregivers.
Bharat Singh Shekhawat+2 more
doaj +1 more source
Aim Although studies in Western countries have investigated the quality of life (QoL) of heroin users, limited research on this topic has been conducted in Asia.
Hu‐Ming Chang+3 more
doaj +1 more source
Personality Traits and Drug Consumption. A Story Told by Data [PDF]
This is a preprint version of the first book from the series: "Stories told by data". In this book a story is told about the psychological traits associated with drug consumption. The book includes: - A review of published works on the psychological profiles of drug users.
arxiv +1 more source
Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]
The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Biersack, H. J.+9 more
core +1 more source