Results 51 to 60 of about 62,557 (287)

Caregiver burden on wives of substance-dependent husbands and its correlates at a Tertiary Care Centre in Northern India

Indian Journal of Public Health, 2017
Background: Substance dependence is well recognized as a complex biopsychosocial phenomenon. Complications arising out of it not only impairs life of substance-dependent patient but also causes enormous burden on their caregivers.
Bharat Singh Shekhawat, Shreyance Jain, Hariom Kumar Solanki   +2 more
doaj   +1 more source

Assessment of sexual behavior among patients seeking treatment for opioid dependence and their knowledge and attitude about high-risk sexual behavior: A cross-sectional observational study

Indian Journal of Social Psychiatry, 2020
Aims: The primary aim of the current study was to assess the sexual history and behavior among treatment-naïve male patients of heroin dependence presenting to outpatient services; their knowledge and attitude about high-risk sexual behavior; and their ...
Nishtha Chawla, Suraj Verma, Siddharth Sarkar, Atul Ambekar   +3 more
doaj   +1 more source

Resting-state Abnormalities in Heroin-dependent Individuals [PDF]

Neuroscience, 2018
Drug addiction is a major health problem worldwide. Recent neuroimaging studies have shed light into the underlying mechanisms of drug addiction as well as its consequences to the human brain. The most vulnerable, to heroin addiction, brain regions have been reported to be specific prefrontal, parietal, occipital, and temporal regions, as well as, some
Pandria, N., Kovatsi, L., Vivas, A.B., Bamidis, P.D.   +3 more
openaire   +3 more sources

Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment

Neuropsychopharmacology Reports, 2023
Aim Although studies in Western countries have investigated the quality of life (QoL) of heroin users, limited research on this topic has been conducted in Asia.
Hu‐Ming Chang, Ming‐Chyi Huang, Su‐Chen Fang, Shih‐Ku Lin   +3 more
doaj   +1 more source

The experience of long-term opiate maintenance treatment and reported barriers to recovery: A qualitative systematic review [PDF]

, 2013
Background/Aim: To inform understanding of the experience of long-term opiate maintenance and identify barriers to recovery. Methods: A qualitative systematic review.
Annie Blyth, Bahna G, Ball JC, Berridge V, Caitlin Notley, Conner KO, De Maeyer J, De Maeyer J, De Maeyer J, Gibson B, Gold ML, Gossop M, Gourlay J, Higgins J, Jarvinen M, Jarvinen M, Jean Craig, McIntosh J, McKeganey N, Moher D, Neale J, Pani PP, Parsons T, Peles E, Richard Holland, Rosenbaum M, Segall A, Skinner ML, Sun AP, Vigilant LG, Vigilant LG, Vivienne Maskrey   +31 more
core   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Allelic and genotypic associations of DRD2 TaqI A polymorphism with heroin dependence in Spanish subjects: a case control study

Behavioral and Brain Functions, 2007
Background Conflicting associations with heroin dependence have been found involving the A1 allele of dopamine D2 receptor gene (DRD2) TaqI A polymorphism.
Calafell Francesc, Banuls Enrique, Volpini Victor, Sinol Nuria, Trujols Joan, Baiget Montserrat, Perez de los Cobos Jose, Luquero Elena, del Rio Elisabeth, Alvarez Enric   +9 more
doaj   +1 more source

Assessing cue-induced brain response as a function of abstinence duration in heroin-dependent individuals: an event-related fMRI study. [PDF]

PLoS ONE, 2013
The brain activity induced by heroin-related cues may play a role in the maintenance of heroin dependence. Whether the reinforcement or processing biases construct an everlasting feature of heroin addiction remains to be resolved.
Qiang Li, Yarong Wang, Yi Zhang, Wei Li, Jia Zhu, Ying Zheng, Jiajie Chen, Liyan Zhao, Zhenyu Zhou, Yijun Liu, Wei Wang, Jie Tian   +11 more
doaj   +1 more source

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh, Eva Saar, Jennifer Pilgrim, Louisa Degenhardt, Lucinda Burns, Suzanne Nielsen, Wayne D Hall   +6 more
core   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source