Results 271 to 280 of about 418,528 (398)

CD4+ tissue‐resident memory T cells and their role in immunity

open access: yesImmunology &Cell Biology, EarlyView.
In this article, we review and discuss the role of CD4+ tissue‐resident memory T (TRM) cells and their role in immune protection in tissues, such as the lungs, by facilitating pathogen clearance through cytokine production and local immune interactions.
Margarida Kirkby, Marc Veldhoen
wiley   +1 more source

Melanoma update: is a cure now in sight?

open access: yesInternal Medicine Journal, EarlyView.
Abstract Melanoma, one of the most aggressive skin cancers, poses a significant global health concern due to its high metastatic potential and resistance to conventional treatments. This review explores recent advancements in melanoma treatment, particularly the impact of targeted therapies and immunotherapies which have significantly extended survival
Samrin Liaqat, Muhammad Adnan Khattak
wiley   +1 more source

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

open access: yesImmunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho   +3 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Erectile dysfunction in dermatology and venereology: From aetiopathogenic mechanisms to practical considerations for dermato‐venereologists

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Multiple inflammatory, infectious and autoimmune dermato‐venereological conditions are associated with erectile dysfunction (ED) due to underlying intricate vasculogenic, neurogenic, endocrine and psychogenic mechanisms. It is recommended that practitioners screen dermatology patients for ED and associated comorbidities, provide personalized lifestyle ...
Andrei Tanasov, George‐Sorin Tiplica
wiley   +1 more source

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