Results 81 to 90 of about 418,528 (398)

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala   +6 more
wiley   +1 more source

Diagnosis of genital herpes simplex virus infection in the clinical laboratory

open access: yesVirology Journal, 2014
Since the type of herpes simplex virus (HSV) infection affects prognosis and subsequent counseling, type-specific testing to distinguish HSV-1 from HSV-2 is always recommended.
J. Legoff, H. Péré, L. Bélec
semanticscholar   +1 more source

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

open access: yesAdvanced Science, EarlyView.
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan   +23 more
wiley   +1 more source

Herpes Simplex Mastitis in an Adolescent Woman: Clinical and Ultrasound Features

open access: yes대한영상의학회지, 2020
Herpetic mastitis is extremely rare, and its imaging findings remain unclear. We report a case of herpes simplex mastitis in an adolescent woman and describe the clinical and ultrasound features.
Seung Kwan Kim   +2 more
doaj   +1 more source

Evolutionary Origins of Human Herpes Simplex Viruses 1 and 2

open access: yesMolecular biology and evolution, 2014
Herpesviruses have been infecting and codiverging with their vertebrate hosts for hundreds of millions of years. The primate simplex viruses exemplify this pattern of virus–host codivergence, at a minimum, as far back as the most recent common ancestor ...
J. Wertheim   +4 more
semanticscholar   +1 more source

Use of oral valaciclovir in a 12-year-old boy with herpes simplex encephalitis [PDF]

open access: yes, 2000
We report on a 12-year-old boy with herpes simplex encephalitis, in whom a severe localised skin reaction developed following the infusion of intravenous acyclovir.
Chan, PKS   +4 more
core  

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang   +9 more
wiley   +1 more source

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

open access: yesAdvanced Science, EarlyView.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen   +8 more
wiley   +1 more source

Acute lymphocytic crisis following herpes simplex type 1 virus hepatitis in a nonimmunocompromised man: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction An increase in circulating lymphocytes can be seen following infections such as infectious mononucleosis and pertussis, or in lymphoproliferative disorders such as acute and chronic lymphocytic leukemia.
Plastiras Sotiris, Kampessi Ourania
doaj   +1 more source

Coping Strategies and Behavioral Changes Following a Genital Herpes Diagnosis Among an Urban Sample of Underserved Midwestern Women [PDF]

open access: yes, 2015
This study focused on understanding the coping strategies and related behavioural changes of women who were recently diagnosed with herpes simplex virus type 2.
Brand, Juanita Ebert   +4 more
core   +1 more source

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