Results 121 to 130 of about 93,644 (200)

Grape constituents for protection against photodamage to skin

open access: yesPhotochemistry and Photobiology, EarlyView.
Excessive exposure to solar ultraviolet radiation has a major negative impact on the health of skin. It causes sunburn, photoaging, keratinocyte carcinomas, and melanomas. Current methods of prevention have failed to stem the incidence of these adverse effects. Grapes are natural products that are being investigated as preventive agents that can impede
Yuri Kwon   +5 more
wiley   +1 more source

Point‐of‐Care Testing by Multiplex‐PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation—Results of a Prospective Study

open access: yesTransplant Infectious Disease, EarlyView.
Use of POCtmPCR with noninvasive samples (NPS and sputum) in LTx recipients with viral LRTI are a viable alternative to invasive BAL sampling, ABSTRACT Background Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality following lung transplantation (LTx).
Susanne Simon   +4 more
wiley   +1 more source

Clinical manifestations of Florida spot keratopathy in dogs and cats: One hundred cases (2021–2024)

open access: yesVeterinary Ophthalmology, EarlyView.
Abstract Purpose This study describes the ocular findings in dogs and cats diagnosed with Florida spot keratopathy (FSK) at a single institution. Methods Affected animals underwent a single comprehensive ophthalmic examination, with no follow‐ups conducted. Data on patient demographics and clinical findings were collected and analyzed. Results Based on
O. Pe'er   +4 more
wiley   +1 more source

Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley   +1 more source

What is chronic urinary tract infection? A systematic review

open access: yesBJU International, Volume 136, Issue 1, Page 12-18, July 2025.
Objective To define ‘chronic’ urinary tract infection (UTI) by reviewing current published research that employs this term. Methods We systematically searched Medline and Embase for studies covering all aspects of human UTI. For comparison, current urological and infectious disease guidelines were also reviewed.
Janni Søvsø Hjelmager   +3 more
wiley   +1 more source

Exploring the Causal Association Between 91 Circulating Inflammatory Proteins and Neurodegenerative Diseases: A Bidirectional Two‐Sample Mendelian Randomization and Bioinformatics Analysis

open access: yesBrain and Behavior, Volume 15, Issue 6, June 2025.
MR analysis evaluates the bidirectional causal relationships between 91 circulating inflammatory proteins and NDDs, contingent upon three critical hypotheses: (1) Correlation hypothesis: SNPs must be strongly correlated with the exposure; (2) Independence hypothesis: SNPs should not be associated with any potential confounding factors; (3) Exclusivity ...
Ziwei Gong, Rong Cao, Hong Zhu
wiley   +1 more source

Fibrotic Fortresses and Therapeutic Frontiers: Pancreatic Stellate Cells and the Extracellular Matrix in Pancreatic Cancer

open access: yesCancer Medicine, Volume 14, Issue 11, June 2025.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by a unique tumor microenvironment (TME) that plays pivotal roles in cancer progression, angiogenesis, metastasis, and drug resistance. This complex and dynamic ecosystem comprises cancer cells, stromal cells, and extracellular matrix (ECM) components, which interact ...
Sila Sigirli, Didem Karakas
wiley   +1 more source

Effective Treatment of Livedoid Vasculopathy With Oral Tofacitinib

open access: yesClinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT We present a woman with severe refractory livedoid vasculopathy who was successfully treated with tofacitinib (5 mg twice a day). The ulcers gradually healed over a period of 2–3 months without experiencing any adverse events over a 1‐year follow‐up period.
Parvin Mansouri, Nikoo Mozafari
wiley   +1 more source

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 11, June 2025.
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao   +4 more
wiley   +1 more source

Analytical treatment interruption among women with HIV in southern Africa who received VRC01 or placebo in the Antibody Mediated Prevention Study: ATI stakeholder engagement, implementation and early clinical data

open access: yesJournal of the International AIDS Society, Volume 28, Issue 6, June 2025.
Abstract Introduction Antiretroviral therapy (ART) prevents and treats, but does not eradicate, HIV. Early ART initiation is associated with post‐ART virologic control, particularly among African women, and anti‐HIV‐1 broadly neutralizing antibodies (bnAbs) may modulate immune responses to HIV.
Shelly Karuna   +30 more
wiley   +1 more source

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