Results 11 to 20 of about 108,460,457 (303)

Herpes Simplex Virus 1 MicroRNAs: An Update

Intervirology, 2023
Background: Herpes simplex virus 1 (HSV-1), an important human pathogen, is capable of latent infection in neurons and productive (lytic) infection in other tissue cells.
Yongzhong Duan, Le Sun, Qihan Li
doaj   +3 more sources

Phenoxazine Derivatives Inactivate Human Cytomegalovirus, Herpes Simplex Virus-1, and Herpes Simplex Virus-2 In Vitro

Journal of Pharmacological Sciences, 2008
We examined whether phenoxazine derivatives, 2-amino-4,4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one (Phx-1), 3-amino-1,4α-dihydro-4α-8-dimethyl-2H-phenoxazine-2-one (Phx-2), and 2-amino-phenoxazine-3-one (Phx-3) may have antiviral activity against ...
Kyoko Hayashi, Toshimitsu Hayashi, Akio Tomoda   +2 more
doaj   +4 more sources

Herpes simplex virus interferes with amyloid precursor protein processing. [PDF]

, 2005
Background The early events underlying Alzheimer's disease (AD) remain uncertain, although environmental factors may be involved. Work in this laboratory has shown that the combination of herpes simplex virus type 1 (HSV1) in brain and carriage of the ...
Shipley, Suzanne J., Parkin, Edward T., Dobson, Curtis B., Itzhaki, Ruth F.   +3 more
core   +6 more sources

A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis [PDF]

Scientific Reports, 2021
AbstractHerpes simplex virus 1 (HSV-1) is responsible for herpes simplex virus encephalitis (HSE), associated with a 70% mortality rate in the absence of treatment. Despite intravenous treatment with acyclovir, mortality remains significant, highlighting the need for new anti-herpetic agents. Herein, we describe a novel neurovirulent recombinant HSV-1 (
Olus Uyar, Pier-Luc Plante, Jocelyne Piret, Marie-Christine Venable, Julie Carbonneau, Jacques Corbeil, Guy Boivin   +6 more
openaire   +3 more sources

Herpes simplex virus type 2: epidemiology and management options in developing countries [PDF]

, 2007
Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical ...
Geretti, AM, Paz-Bailey, G., Ramaswamy, M., Paz-Bailey, G, Hawkes, SJ, Hawkes, S. J., Geretti, A. M., Ramaswamy, M   +7 more
core   +1 more source

Herpes simplex virus triggers and then disarms a host antiviral response [PDF]

, 2001
Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human ...
Smiley, J R, Macgregor, P F, Edwards, A M, Mossman, K L, Rozmus, J J, Goryachev, A B   +5 more
core   +1 more source

A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]

, 2012
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Rixon Frazer J., Schmid Michael F., Rixon, Frazer J., Bhella David, David Bhella, Ryan H. Rochat (129683), Hecksel, Corey W., Rochat, Ryan H., Hecksel Corey W., Chiu Wah, Bhella, David, Chiu, Wah, Wah Chiu, Michael F. Schmid (129681), Michael F Schmid, Rochat Ryan H., Corey W Hecksel, Schmid, Michael F., David Bhella (129684), Frazer J. Rixon (129686), Frazer J Rixon, Corey W. Hecksel (129682), Ryan H Rochat, Wah Chiu (129685)   +23 more
core   +1 more source

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]

, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu, Frazer J. Rixon, Petermann, P., Rixon Frazer J., Rahn, E., Hsu Mei-Ju, Knebel-Mörsdorf, D., Geraghty, R.J., Dagmar Knebel-Mörsdorf, Rahn Elena, Philipp Petermann, Knebel-Mörsdorf Dagmar, Elena Rahn, Frazer J Rixon, Hsu, M.-J., Rixon, F.J., Petermann Philipp   +16 more
core   +1 more source

Double encephalitis with herpes simplex virus type II and cytomegalovirus in an elder Chinese: a case report

Neuropsychiatric Disease and Treatment, 2015
Chaobiao Xue,1,2 Shaoxian Chen,1 Qi Lin,1 Houshi Zhou,1 Chuming Huang,1 Jiyuan Lin,1 Weihang Xie,1 Kai Chen,1 Dongming Zhou,1 Wan Ma,1 Feiyu Ma,1 Haiyun Xu2 1Outpatient Department, Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen ...
Xue C, Chen S, Lin Q, Zhou H, Huang C, Lin J, Xie W, Chen K, Zhou D, Ma W, Ma F, Xu H   +11 more
doaj   +1 more source

Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]

, 2007
BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre, Van de Perre, Philippe, Sanon, Anselme, Segondy, Michel, Weiss, Helen A, Andonaba, Jean-Baptiste, Vallo, Roselyne, ANRS 1285 Study Group, Sawadogo, Adrien, Nagot, Nicolas, Foulongne, Vincent, Vergne, Laurence, Mayaud, Philippe, Ouédraogo, Abdoulaye, Defer, Marie-Christine, Djagbaré, Didier, Konaté, Issouf   +16 more
core   +1 more source