Results 41 to 50 of about 108,460,457 (303)

Reply to “Herpes Simplex Virus 1, Macrophages, and the Cornea” [PDF]

Journal of Virology, 2017
In a letter to the editor regarding our report in the Journal of Virology (JVI) ([1][1]), several issues were raised by Daniel Carr, and our responses to his points are as follows. (i) Dr. Carr, in support of his comments, cites papers by Tumpey et al. ([2][2]) and Thomas et al. ([3][3]). However,
Dhong Hyun, Lee, Homayon, Ghiasi
openaire   +2 more sources

Population-level effect of potential HSV2 prophylactic vaccines on HIV incidence in sub-Saharan Africa. [PDF]

, 2009
Herpes simplex virus type-2 (HSV2) infection increases HIV transmission. We explore the impact of a potential prophylactic HSV2 vaccination on HIV incidence in Africa using STDSIM an individual-based model.
Orroth, K. K., Buve, A, Weiss, Helen A, Hayes, R. J., Glynn, Judith R, Weiss, H. A., White, Richard G, Hayes, Richard J, Bakker, R., Orroth, Kate K, Buvé, Anne, Freeman, EE, Glynn, J. R., Weiss, HA, White, R. G., Freeman, Esther E, Freeman, E. E., Buvé, A., White, RG, Glynn, JR, Orroth, KK, Bakker, Roel, Hayes, RJ   +22 more
core   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Increased carotid intima-media thickness associated with antibody responses to varicella-zoster virus and cytomegalovirus in HIV-infected patients. [PDF]

PLoS ONE, 2013
OBJECTIVE: We investigated the relationship of the Herpesviridiae with inflammation and subclinical atherosclerosis in HIV-infected patients. METHODS: Prospective study including virologically suppressed HIV-infected patients.
Mar Masiá, Catalina Robledano, Victoria Ortiz de la Tabla, Pedro Antequera, Natividad López, Félix Gutiérrez   +5 more
doaj   +1 more source

Stromal Keratitis among Herpes Simplex Keratitis Patients in a Tertiary Eye Hospital: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2022
Introduction: The manifestations of herpes simplex virus keratitis range from epithelial keratitis to vision-threatening stromal keratitis. There are limited studies done on our part regarding stromal keratitis.
Poonam Shrestha, Santosh Paudel
doaj   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Control of herpes simplex virus type 1 latency in human trigeminal ganglia [PDF]

, 2012
Herpes simplex virus type 1 (HSV-1) is a double-stranded DNA virus that infects humans and, after a primary lytic infection, establishes lifelong latency in the sensory neurons of the trigeminal ganglia (TG).
Held, Kathrin, Held, K.
core   +1 more source

A successfully treated case of herpes simplex encephalitis complicated by subarachnoid bleeding: a case report

Journal of Medical Case Reports, 2010
Introduction Histopathologically, herpes simplex virus type 1 causes hemorrhagic necrosis. Overt hemorrhage is infrequent in herpes simplex virus encephalitis but can lead to poor outcomes.
Okuchi Kazuo, Kawahara Makoto, Yata Noritaka, Kataoka Hiroshi, Tonomura Yasuyo, Ueno Satoshi   +5 more
doaj   +1 more source

Herpes Simplex Virus 1 Induces Microglia Gasdermin D-Dependent Pyroptosis Through Activating the NLR Family Pyrin Domain Containing 3 Inflammasome

Frontiers in Microbiology, 2022
Herpes simplex virus type 1 (HSV-1) is a highly prevalent virus in humans and causes severe forms of inflammation, such as herpes simplex encephalitis (HSE).
Xiao Hu, Xiao Hu, Xiao Hu, Xiao Hu, Xiao Hu, Xiao Hu, Qiongzhen Zeng, Qiongzhen Zeng, Qiongzhen Zeng, Qiongzhen Zeng, Qiongzhen Zeng, Ji Xiao, Ji Xiao, Ji Xiao, Ji Xiao, Ji Xiao, Shurong Qin, Shurong Qin, Shurong Qin, Shurong Qin, Shurong Qin, Shurong Qin, Yuan Wang, Yuan Wang, Yuan Wang, Yuan Wang, Yuan Wang, Tianhao Shan, Tianhao Shan, Tianhao Shan, Tianhao Shan, Tianhao Shan, Di Hu, Di Hu, Di Hu, Di Hu, Di Hu, Di Hu, Yexuan Zhu, Yexuan Zhu, Yexuan Zhu, Yexuan Zhu, Yexuan Zhu, Kaisheng Liu, Kai Zheng, Yifei Wang, Yifei Wang, Yifei Wang, Yifei Wang, Yifei Wang, Zhe Ren, Zhe Ren, Zhe Ren, Zhe Ren, Zhe Ren   +54 more
doaj   +1 more source