Results 31 to 40 of about 108,460,457 (303)

Atypical presentation of herpes simplex virus type 1 infection in paediatric burns patients in a large tertiary hospital, South Africa

African Journal of Laboratory Medicine, 2019
Introduction: Herpes simplex virus has been reported in the literature to commonly complicate burn wounds. However, there is paucity of such data in the South African setting.
Mpho L. Sikhosana, Asma Salloo, Monica Birkhead, Kerrigan McCarthy   +3 more
doaj   +1 more source

On the Mutation Rate of Herpes Simplex Virus Type 1 [PDF]

Genetics, 2005
Abstract All seven DNA-based microbes for which carefully established mutation rates and mutational spectra were previously available displayed a genomic mutation rate in the neighborhood of 0.003 per chromosome replication. The pathogenic mammalian DNA virus herpes simplex type 1 has an estimated genomic mutation rate compatible with ...
John W, Drake, Charles B C, Hwang
openaire   +2 more sources

Seroprevalence, predictors and estimated incidence of maternal and neonatal Herpes Simplex Virus Type 2 infection in semi-urban women in Kilifi, Kenya [PDF]

, 2011
Background: Herpes Simplex Virus type 2 (HSV-2) has public health importance as a leading cause of genital ulcers, a co-factor in HIV-1 acquisition and transmission and as a cause of neonatal herpes infections.
Awuondo Ken, Pauli N Amornkul, Nyiro Joyce U, Ngetsa, Caroline, Amornkul Pauli N, Amornkul, Pauli N., Wale, Steve, Caroline Ngetsa, James Nokes D, Price Matthew A, Elizabeth Bukusi, Price, Matthew A., Joyce U Nyiro, Ngetsa Caroline, Bukusi, Elizabeth Anne, Bukusi Elizabeth, Nokes, D. James, Awuondo, Ken, Wale Steve, Ken Awuondo, D James Nokes, Sanders Eduard J, Nyiro, Joyce U., Eduard J Sanders, Matthew A Price, Sanders, Eduard J., Steve Wale   +26 more
core   +2 more sources

Challenges for early diagnosis of neonatal herpes infection in Japan

Frontiers in Reproductive Health
BackgroundThis study aimed to analyze the recent prevalence of neonatal herpes simplex virus infection, maternal symptoms in the presence of neonate who has herpes simplex virus infection, and mode of delivery in Japan.MethodsWe requested 2.078 ...
Junya Kojima, Shunji Suzuki, Shin-Ichi Hoshi, Akihiko Sekizawa, Yoko Sagara, Hideo Matsuda, Isamu Ishiwata, Tadaichi Kitamura   +7 more
doaj   +1 more source

Herpes simplex virus type 2 trends in relation to the HIV epidemic in northern Malawi. [PDF]

, 2008
OBJECTIVES: It is unclear whether the high prevalence of herpes simplex virus type 2 (HSV-2) found in much of Africa predates the HIV epidemic or is, to some extent, a consequence of it.
Fine, P.E.M., Glynn, JR, Glynn, J.R., Mwanyongo, O., Crampin, A.C., Crampin, AC, Ngwira, B.M.M., Ngwira, BMM, Ndhlovu, R., Mwanyongo, O, Fine, PEM, Ndhlovu, R   +11 more
core   +1 more source

Herpes Simplex Virus 1 Deregulation of Host MicroRNAs [PDF]

Non-Coding RNA, 2018
Viruses utilize microRNAs (miRNAs) in a vast variety of possible interactions and mechanisms, apparently far beyond the classical understanding of gene repression in humans. Likewise, herpes simplex virus 1 (HSV-1) expresses numerous miRNAs and deregulates the expression of host miRNAs.
Maja Cokarić Brdovčak, Andreja Zubković, Igor Jurak   +2 more
openaire   +3 more sources

UBE1a Suppresses Herpes Simplex Virus-1 Replication [PDF]

Viruses, 2020
Herpes simplex virus-1 (HSV-1) is the causative agent of cold sores, keratitis, meningitis, and encephalitis. HSV-1-encoded ICP5, the major capsid protein, is essential for capsid assembly during viral replication. Ubiquitination is a post-translational modification that plays a critical role in the regulation of cellular events such as proteasomal ...
Marina Ikeda, Akihiro Ito, Yuichi Sekine, Masahiro Fujimuro   +3 more
openaire   +3 more sources

Interleukin 1β receptor and synaptic dysfunction in recurrent brain infection with Herpes simplex virus type-1

Neural Regeneration Research
Several experimental evidence suggests a link between brain Herpes simplex virus type-1 infection and the occurrence of Alzheimer’s disease. However, the molecular mechanisms underlying this association are not completely understood.
Roberto Piacentini, Claudio Grassi
doaj   +1 more source

The Dynamics of HCF-1 Modulation of Herpes Simplex Virus Chromatin during Initiation of Infection

Viruses, 2013
Successful infection of herpes simplex virus is dependent upon chromatin modulation by the cellular coactivator host cell factor-1 (HCF-1). This review focuses on the multiple chromatin modulation components associated with HCF-1 and the chromatin ...
Thomas M. Kristie, Jodi L. Vogel
doaj   +1 more source

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Mascolo, Andrea, Arbusow, Viktor, Theil, Diethilde, Brandt, Thomas, Strupp, Michael   +4 more
core   +1 more source