Results 21 to 30 of about 18,603 (132)

Next⁃generation sequencing technology in the diagnosis of five patients with human herpesvirus encephalitis/meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To evaluate the value of next⁃generation sequencing (NGS) of cerebrospinal fluid (CSF) in the diagnosis of human herpesvirus encephalitis/meningitis.
Ke JIN, Xiao-juan WANG, Hong-zhi GUAN, Ling-zhi QIN, Ya-zhen JIA, Ke-ke ZHOU, Hai-chang MA, Yue WANG, Fang WANG, Li XING, Wei LI   +10 more
doaj  

Varicella infection in an immunized pediatric living donor liver-transplant recipient

Journal of Global Infectious Diseases, 2021
Varicella-zoster virus (VZV) is a DNA virus belonging to the Herpesviridae family. Primary infection causes chickenpox followed by latency in the sensory ganglia, which can sometimes reactivate leading to herpes zoster.
Vibha Mehta, Krithiga Ramachandran, Reshu Agarwal, Seema Alam, Viniyendra Pamecha, Ekta Gupta   +5 more
doaj   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Unveiling the Impact of Human Herpesviruses-Associated on CNS Infections: An Observational Study

Viruses
Human Herpesviruses (HHVs) play a significant role in neurological diseases such as encephalitis and meningitis, adding significant morbidity. This study aims to retrospectively analyze the effect of HHVs on patients with neurological symptoms, focusing ...
Caio Cesar L. B. Barrionuevo, Pedro P. A. Baptista, Ewerton F. da Silva, Bernardo M. da Silva, Cássia da L. Goulart, Sabrina A. de Melo, Valderjane A. da Silva, Lara Laycia A. de Souza, Rossicleia L. Monte, Fernando F. Almeida-Val, Pablo Vinícius S. Feitoza, Michele de S. Bastos   +11 more
doaj   +1 more source

16S/18S metabarcoding versus culture for aetiological assessment in infectious keratitis: A prospective paired‐sample study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Infectious keratitis (IK) is a vision‐threatening condition with diverse microbial aetiologies, yet conventional culture‐based diagnostics often have limited sensitivity. We investigated whether 16S/18S rRNA amplicon‐based next‐generation sequencing (NGS) can enhance aetiological assessment when used alongside standard microbiological ...
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Lise Kristensen, Anders Ivarsen   +6 more
wiley   +1 more source

Adoptive Immunotherapy for Prophylaxis and Treatment of Cytomegalovirus Infection

Viruses, 2022
Cytomegalovirus (CMV), a member of the Herpesviridae family, is frequent among hematopoietic cell transplant (HCT) and solid organ transplant (SOT) recipients in absence of antiviral prophylaxis, and is a major cause of morbidity and mortality in these ...
Christopher P. Ouellette
doaj   +1 more source

Advances in Cytosolic dsRNA Sensing of Viral Infections

Immunology &Cell Biology, EarlyView.
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley   +1 more source

The role of the Herpesviridae family in the development of Long COVID

Annals of Mechnikov's Institute
The aim of this study was to investigate the activity of viruses from the Herpesviridae family in the leukocytes of patients with long COVID. Materials and Methods. Following a case-control design, the study included 52 patients with long COVID (Group 1).
Олена Грішина, Ольга Романенко, Олена Менкус   +2 more
doaj   +1 more source

Implications of Microorganisms in Alzheimer’s Disease

Current Issues in Molecular Biology, 2022
Alzheimer’s disease (AD) is a deadly brain degenerative disorder that leads to brain shrinkage and dementia. AD is manifested with hyperphosphorylated tau protein levels and amyloid beta (Aβ) peptide buildup in the hippocampus and cortex regions of the ...
Pardeep Yadav, Yeon-Hee Lee, Hrithika Panday, Shubham Kant, Neha Bajwa, Ritika Parashar, Saurabh Kumar Jha, Niraj Kumar Jha, Parma Nand, Sang-Soo Lee, Abhimanyu Kumar Jha   +10 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source