Results 41 to 50 of about 18,603 (132)
We have previously shown that Epstein-Barr virus (EBV)-encoded dUTPase can modulate innate immune responses through the activation of TLR2 and NF-kappaB signaling. However, whether this novel immune function of the dUTPase is specific for EBV or a common
Maria Eugenia eAriza +2 more
doaj +1 more source
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann +3 more
wiley +1 more source
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh +8 more
wiley +1 more source
Twenty‐one compounds, including six dolabellanes diterpenes and one germacrene sesquiterpene that are new natural products, are reported from the brown algae Dictyota fasciola and Dictyota mediterranea collected from the Aegean Sea. Among them, some exhibit considerable antiviral activity against RNA (HCoV‐NL63, ZIKV) and DNA (HSV‐1) viruses.
Aikaterini Koutsaviti +10 more
wiley +1 more source
ABSTRACT Ramsay Hunt syndrome, caused by varicella‐zoster virus reactivation, presents with facial paralysis, otalgia, and auricular vesicles. A Tanzanian woman with Grade VI facial palsy was treated with acyclovir and prednisolone, recovering to Grade II within 2 weeks.
Jacob Henry Kitundu +4 more
wiley +1 more source
Periodontal diseases in pediatric subjects represent a challenging and relatively underexplored area compared to the extensive data available about periodontal diseases in adults.
Federica Di Spirito +7 more
doaj +1 more source
Lung Microbiome Diversity, Infection Dynamics, and Microbe‐Mediated Cross‐Protection
The protective role of the lung microbiome in maintaining respiratory health by promoting immune homeostasis, pathogen exclusion, and barrier integrity. Diverse microbial communities regulate immune maturation, enhance epithelial defenses, and contribute to antiviral responses, collectively preventing pathogen colonization and sustaining a balanced ...
Sana Arooj +7 more
wiley +1 more source
Background Pneumocystis jirovecii (P. jirovecii) is an opportunistic fungus responsible for Pneumocystis pneumonia (PCP) in deeply immunocompromised patients and for pulmonary colonization in individuals with mild immunosuppression or impaired ...
Alan Rucar +4 more
doaj +1 more source
Opportunistic infections in pediatrics: when to suspect and how to approach
Objectives: To describe the characteristics of opportunistic infections in pediatrics regarding their clinical aspects, as well as the diagnostic strategy and treatment.
Maria Isabel de Moraes-Pinto +1 more
doaj +1 more source
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss +9 more
wiley +1 more source

