Results 41 to 50 of about 18,603 (132)

Human Herpesviruses-encoded dUTPases: A Family of Proteins that Modulate Dendritic Cell Function and Innate Immunity

open access: yesFrontiers in Microbiology, 2014
We have previously shown that Epstein-Barr virus (EBV)-encoded dUTPase can modulate innate immune responses through the activation of TLR2 and NF-kappaB signaling. However, whether this novel immune function of the dUTPase is specific for EBV or a common
Maria Eugenia eAriza   +2 more
doaj   +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 7, Page 1967-1975, July 2026.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann   +3 more
wiley   +1 more source

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1283-1288, June 2026.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh   +8 more
wiley   +1 more source

Isolation of Metabolites With Antiviral Activity From the Brown Algae Dictyota fasciola and Dictyota mediterranea

open access: yesChemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Twenty‐one compounds, including six dolabellanes diterpenes and one germacrene sesquiterpene that are new natural products, are reported from the brown algae Dictyota fasciola and Dictyota mediterranea collected from the Aegean Sea. Among them, some exhibit considerable antiviral activity against RNA (HCoV‐NL63, ZIKV) and DNA (HSV‐1) viruses.
Aikaterini Koutsaviti   +10 more
wiley   +1 more source

Rapid Resolution of Grade VI Facial Nerve Paralysis in Ramsay Hunt Syndrome With Prompt Dual Antiviral‐Corticosteroid Therapy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Ramsay Hunt syndrome, caused by varicella‐zoster virus reactivation, presents with facial paralysis, otalgia, and auricular vesicles. A Tanzanian woman with Grade VI facial palsy was treated with acyclovir and prednisolone, recovering to Grade II within 2 weeks.
Jacob Henry Kitundu   +4 more
wiley   +1 more source

Periodontal Microbial Profiles Across Periodontal Conditions in Pediatric Subjects: A Narrative Review

open access: yesMicroorganisms
Periodontal diseases in pediatric subjects represent a challenging and relatively underexplored area compared to the extensive data available about periodontal diseases in adults.
Federica Di Spirito   +7 more
doaj   +1 more source

Lung Microbiome Diversity, Infection Dynamics, and Microbe‐Mediated Cross‐Protection

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The protective role of the lung microbiome in maintaining respiratory health by promoting immune homeostasis, pathogen exclusion, and barrier integrity. Diverse microbial communities regulate immune maturation, enhance epithelial defenses, and contribute to antiviral responses, collectively preventing pathogen colonization and sustaining a balanced ...
Sana Arooj   +7 more
wiley   +1 more source

Pulmonary co-infections by Pneumocystis jirovecii and Herpesviridae: a seven-year retrospective study

open access: yesAnnals of Clinical Microbiology and Antimicrobials
Background Pneumocystis jirovecii (P. jirovecii) is an opportunistic fungus responsible for Pneumocystis pneumonia (PCP) in deeply immunocompromised patients and for pulmonary colonization in individuals with mild immunosuppression or impaired ...
Alan Rucar   +4 more
doaj   +1 more source

Opportunistic infections in pediatrics: when to suspect and how to approach

open access: yesJornal de Pediatria (Versão em Português), 2020
Objectives: To describe the characteristics of opportunistic infections in pediatrics regarding their clinical aspects, as well as the diagnostic strategy and treatment.
Maria Isabel de Moraes-Pinto   +1 more
doaj   +1 more source

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

open access: yesAdvanced Science, Volume 13, Issue 28, 18 May 2026.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss   +9 more
wiley   +1 more source

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