Results 41 to 50 of about 17,962 (174)

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection [PDF]

Neuron, 2018
Amyloid-β peptide (Aβ) fibrilization and deposition as β-amyloid are hallmarks of Alzheimer's disease (AD) pathology. We recently reported Aβ is an innate immune protein that protects against fungal and bacterial infections. Fibrilization pathways mediate Aβ antimicrobial activities.
William A, Eimer, Deepak Kumar, Vijaya Kumar, Nanda Kumar, Navalpur Shanmugam, Alex S, Rodriguez, Teryn, Mitchell, Kevin J, Washicosky, Bence, György, Xandra O, Breakefield, Rudolph E, Tanzi, Robert D, Moir   +9 more
openaire   +3 more sources

Next⁃generation sequencing technology in the diagnosis of five patients with human herpesvirus encephalitis/meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To evaluate the value of next⁃generation sequencing (NGS) of cerebrospinal fluid (CSF) in the diagnosis of human herpesvirus encephalitis/meningitis.
Ke JIN, Xiao-juan WANG, Hong-zhi GUAN, Ling-zhi QIN, Ya-zhen JIA, Ke-ke ZHOU, Hai-chang MA, Yue WANG, Fang WANG, Li XING, Wei LI   +10 more
doaj  

Varicella infection in an immunized pediatric living donor liver-transplant recipient

Journal of Global Infectious Diseases, 2021
Varicella-zoster virus (VZV) is a DNA virus belonging to the Herpesviridae family. Primary infection causes chickenpox followed by latency in the sensory ganglia, which can sometimes reactivate leading to herpes zoster.
Vibha Mehta, Krithiga Ramachandran, Reshu Agarwal, Seema Alam, Viniyendra Pamecha, Ekta Gupta   +5 more
doaj   +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann, Cecilie Klausen, Michael Karbiener, Thomas R. Kreil   +3 more
wiley   +1 more source

Adoptive Immunotherapy for Prophylaxis and Treatment of Cytomegalovirus Infection

Viruses, 2022
Cytomegalovirus (CMV), a member of the Herpesviridae family, is frequent among hematopoietic cell transplant (HCT) and solid organ transplant (SOT) recipients in absence of antiviral prophylaxis, and is a major cause of morbidity and mortality in these ...
Christopher P. Ouellette
doaj   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

Wildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie, Luyao Wang, Mengna Chen, Qinjie Chang, Hongyu Jiang, Haitao Xu, Liu Dan, Xiang Li, Yulong Wang, Xiangwei Zeng, Bin Yang, Miaowei Wang, Yonggang Jiang, Hongliang Chai, Siyuan Yang, Yajun Wang   +15 more
wiley   +1 more source

The role of the Herpesviridae family in the development of Long COVID

Annals of Mechnikov's Institute
The aim of this study was to investigate the activity of viruses from the Herpesviridae family in the leukocytes of patients with long COVID. Materials and Methods. Following a case-control design, the study included 52 patients with long COVID (Group 1).
Андрій Волянський, Олена Грішина, Ольга Романенко, Олена Менкус   +3 more
doaj   +1 more source

Implications of Microorganisms in Alzheimer’s Disease

Current Issues in Molecular Biology, 2022
Alzheimer’s disease (AD) is a deadly brain degenerative disorder that leads to brain shrinkage and dementia. AD is manifested with hyperphosphorylated tau protein levels and amyloid beta (Aβ) peptide buildup in the hippocampus and cortex regions of the ...
Pardeep Yadav, Yeon-Hee Lee, Hrithika Panday, Shubham Kant, Neha Bajwa, Ritika Parashar, Saurabh Kumar Jha, Niraj Kumar Jha, Parma Nand, Sang-Soo Lee, Abhimanyu Kumar Jha   +10 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Lys-specific gingipain (Kgp) of P. gingivalis promotes viral infection by disabling the interferon pathway

mBio
Periodontitis (PD) is a chronic inflammatory disease of the periodontium with a high prevalence and is considered a potential risk factor for the development of other diseases.
Ewelina Dobosz, Anna Golda, Michal Kanoza, Weronika Kowalczuk, Barbara Potempa, Jan Potempa, Anna Gasiorek, Natalia Madeja, Joanna Budziaszek, Danuta Mizgalska, Tulay Yucel-Lindberg, Joanna Koziel   +11 more
doaj   +1 more source