Results 51 to 60 of about 817,417 (222)

Targeting Host Cellular Factors as a Strategy of Therapeutic Intervention for Herpesvirus Infections

Frontiers in Cellular and Infection Microbiology, 2021
Herpesviruses utilize various host factors to establish latent infection, survival, and spread disease in the host. These factors include host cellular machinery, host proteins, gene expression, multiple transcription factors, cellular signal pathways ...
Kumari Asha, Neelam Sharma-Walia
doaj   +1 more source

Partial characterisation of pilchard herpesvirus and the associated disease in pilchards [PDF]

, 2007
In 1995 and again in 1998, millions of pilchards (Sardinops sagax neopilchardus) were found dead or dying off the coast of Australia and also in New Zealand. The epizootics moved progressively, at a rapid speed against the prevailing currents.
Crockford, Melanie
core  

Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]

, 2009
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr, Ulrich Koszinowski, Mühlbach, Hermine, Koszinowski, Ulrich H., Zsolt Ruzsics, Christian Mohr, Mohr, Christian A., Ruzsics, Zsolt, Hermine Mühlbach, Ulrich H. Koszinowski   +9 more
core   +1 more source

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source

Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions

Pathogens, 2020
We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy.
Laura Gallina, Federica Savini, Sabrina Canziani, Matteo Frasnelli, Antonio Lavazza, Alessandra Scagliarini, Davide Lelli   +6 more
doaj   +1 more source

A practical difference from the normal approach to evaluate natural killer (NK) cells and NK cell neoplasms by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Natural killer (NK) cell neoplasms span indolent to highly aggressive entities, and flow cytometric immunophenotyping is central to their detection and classification. However, distinguishing reactive from neoplastic NK cell expansions can be challenging because NK cells lack somatically recombined antigen receptors, and reactive states may ...
Aaron J. Wilk, Afshin Shameli, Erik Ames, Jonathan R. Fromm, Bartosz Grzywacz, Min Shi, Sindhu Cherian, Jean Oak   +7 more
wiley   +1 more source

Viral Infections in Burn Patients: A State-Of-The-Art Review

Viruses, 2020
Infections that are triggered by the accompanying immunosuppression in patients with burn wounds are very common regardless of age. Among burn patients, the most frequently diagnosed infections include the bacterial ones primarily caused by Pseudomonas ...
Jacek Baj, Izabela Korona-Głowniak, Grzegorz Buszewicz, Alicja Forma, Monika Sitarz, Grzegorz Teresiński   +5 more
doaj   +1 more source

The HHV-6A Proteins U20 and U21 Target NKG2D Ligands to Escape Immune Recognition

Frontiers in Immunology, 2021
The coevolution of the human immune system and herpesviruses led to the emergence and diversification of both cellular danger molecules recognized by immune cells on the one hand and viral countermeasures that prevent the expression of these proteins on ...
Abigael Eva Chaouat, Barbara Seliger, Barbara Seliger, Ofer Mandelboim, Dominik Schmiedel, Dominik Schmiedel   +5 more
doaj   +1 more source

A beta-herpesvirus with fluorescent capsids to study transport in living cells. [PDF]

, 2012
Fluorescent tagging of viral particles by genetic means enables the study of virus dynamics in living cells. However, the study of beta-herpesvirus entry and morphogenesis by this method is currently limited.
Lisa Marcinowski, Marcinowski, Lisa, Ulrich H Koszinowski, Christophe Jung (152124), Jens von Einem, Gaul, Ulrike, Paul Walther, Einem, Jens von, Jens B Bosse, Paul Walther (113867), Ruzsics, Zsolt, Ulrike Gaul, Ulrich H. Koszinowski (152143), Bosse, Jens B., Zsolt Ruzsics (75383), Leonhard Popilka (152101), Leonhard Popilka, Christophe Jung, Jens B. Bosse (138966), Lisa Marcinowski (138962), Jens B. Bosse, Martina Taeglich (152115), Rudolf Bauerfeind (152093), Taeglich, Martina, Koszinowski, Ulrich H., Hannah Striebinger, Zsolt Ruzsics, Ulrike Gaul (3154), Ulrich H. Koszinowski, Jung, Christophe, Hannah Striebinger (152128), Martina Taeglich, Jens von Einem (152134), Bauerfeind, Rudolf, Striebinger, Hannah, Rudolf Bauerfeind, Walther, Paul, Popilka, Leonhard, Jung Christophe, Taeglich Martina, Bosse Jens B., Popilka Leonhard, Bauerfeind Rudolf, Marcinowski Lisa, Walther Paul, Striebinger Hannah, von Einem Jens, Koszinowski Ulrich H., Ruzsics Zsolt, Gaul Ulrike   +49 more
core   +2 more sources

Diagnostic Usefulness of Cell Block Samples in Fluid Overload‐Associated Large B‐Cell Lymphoma

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Hiroyuki Okanishi, Hiroko Kuwabara, Hiroko Nakayama, Mayo Odaka, Kozue Ariga, Isako Kataoka, Mari Tomiuka, Mayumi Uragami, Chihiro Deguchi, Shizuka Ono, Reika Takeda, Yoshitaka Kurisu, Yoshinobu Hirose, Yuuki Kinoshita, Taiji Yokote   +14 more
wiley   +1 more source