Results 71 to 80 of about 765,960 (222)
Emerging Paediatric Uses of Dupilumab Beyond Approvals
Clinical &Experimental Allergy, EarlyView.Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese +11 more
wiley +1 more source
Clinical and genetic characterization of intellectual disability
Developmental Medicine &Child Neurology, EarlyView.This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara +14 more
wiley +1 more source
Viruses, 2016 In recent years, it has been suggested that host cells exert intrinsic mechanisms to control nuclear replicating DNA viruses. This cellular response involves nuclear antiviral factors targeting incoming viral genomes.
Tetsuro Komatsu +2 more
doaj +1 more source
HIV Medicine, EarlyView.Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart +10 more
wiley +1 more source
When to consider an inborn error of immunity: clues for physicians
Internal Medicine Journal, EarlyView.Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Asymptomatic Violaceous Papules of the Penis in a Patient With HIV
JEADV Clinical Practice, EarlyView.
Jhon Edwin Rodríguez‐Vásquez +5 more
wiley +1 more source
Journal of Fish Biology, EarlyView.Abstract In open marine aquaculture, rearing diverse fish species in adjacent net pens facilitates the waterborne spread of red sea bream iridovirus (RSIV). This study systematically evaluated the horizontal transmission dynamics of RSIV in black sea bream (BSB, Acanthopagrus schlegelii) and Japanese sea bass (JS, Lateolabrax japonicus) under immersion
Chae‐yeong Ji +5 more
wiley +1 more source
Fish Poxviruses on the Rise: Prospects for Aquatic Health
Journal of Fish Diseases, EarlyView.ABSTRACT Fish poxviruses are increasingly recognised as emerging pathogens of fish and should be considered in cases of unexplained gill or skin pathology. Carp edema virus (CEV), the causative agent of koi sleepy disease in common carp and koi (Cyprinus carpio), represents the first known example.
Mikolaj Adamek +9 more
wiley +1 more source