Multiple human herpesvirus-8 infection [PDF]
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM+7 more
core +1 more source
Viral epidemics in a cell culture: novel high resolution data and their interpretation by a percolation theory based model [PDF]
Because of its relevance to everyday life, the spreading of viral infections has been of central interest in a variety of scientific communities involved in fighting, preventing and theoretically interpreting epidemic processes. Recent large scale observations have resulted in major discoveries concerning the overall features of the spreading process ...
arxiv +1 more source
Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan+3 more
core +2 more sources
Human herpesvirus 1 meningoencephalitis after trigeminal neuralgia surgery
We report a case of human herpesvirus 1 (HHV-1) meningoencephalitis in a patient who underwent trigeminal neuralgia surgery. Although this surgery has been reported to increase the risk of mucocutaneous HHV-1 recurrence, to our knowledge, an association between trigeminal surgery and HHV-1 encephalitis has not been previously described.
Núria Prim+5 more
openaire +4 more sources
Analysis of the human herpesvirus-6 immediate-early 1 protein
Herpesvirus immediate-early (IE) gene products play key roles in establishing productive infections, regulating reactivation from latency and evading immune recognition. Analyses of HHV-6 IE gene expression have revealed that the IE1 gene of the HHV-6A and HHV-6B variants exhibits a higher degree of sequence variation than other regions of the genome ...
Julie D. Fox+4 more
openaire +3 more sources
Virucidal Efficacy of Laser-Generated Copper Nanoparticle Coatings Against Model Coronavirus and Herpesvirus [PDF]
High-efficiency antiviral surfaces can be effective means to fight against viral diseases such as the recent Covid-19 pandemic. Copper and copper oxides, as well as their nanoparticles (Cu NPs) and coatings, are among the effective antiviral materials having internal and external biocidal effects on viruses.
arxiv
Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark+5 more
core +1 more source
Human Herpesvirus 8 Reactivation and Human Immunodeficiency Virus Type 1 gp120
Abstract Context.—Human herpesvirus 8 (HHV-8) is the presumed etiologic agent of Kaposi sarcoma (KS), the most common neoplasm in patients with acquired immunodeficiency syndrome. Current evidence indicates HHV-8 is necessary, but not sufficient, for KS development without the involvement of other cofactors.
Kimberly E. Foreman+4 more
openaire +3 more sources
Seroprevalence of Human Herpesvirus-8 in HIV-1 Infected and Uninfected Individuals in Cameroon [PDF]
We evaluated the prevalence of HHV-8 antibodies in 516 plasma samples collected from HIV positive and negative patients from blood banks and urban areas of Cameroon. Among HIV-1 positive samples, HHV-8 seropositivity rate was 61% based on combined reactivity using both ELISA and IFA techniques.
Christelle Mbondji-Wonje+5 more
openaire +4 more sources
Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
BM Friedman+51 more
core +2 more sources