Results 1 to 10 of about 87,372 (235)
Human Herpesvirus-6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult. [PDF]
Brain BehavHuman Herpesvirus‐6 infectious meningitis with lymphadenitis in an immunocompetent adult. CSF: cerebrospinal fluid; NGS: next‐generation sequencing; HHV‐6: Human herpes virus‐6 ABSTRACT Purpose Human Herpesvirus 6 (HHV‐6) infections are primarily observed in immunocompromised individuals, such as those with acquired immunodeficiency syndrome or organ ...
Xie Y +9 more
europepmc +2 more sources
Inherited IRAK-4 Deficiency in Acute Human Herpesvirus-6 Encephalitis
Journal of Clinical Immunology, 2022 Human herpesvirus-6 (HHV-6) infection can rarely cause life-threatening conditions, such as encephalitis, in otherwise healthy children, with unclear pathogenesis. We studied a child who presented with acute HHV-6 encephalitis at the age of 10 months and who was homozygous for a novel missense mutation in IRAK4, encoding interleukin-1 receptor ...
Zeynep Güneş Tepe +6 more
openaire +5 more sources
Evidence of Human Herpesvirus 6 Infection in 4 Immunocompetent Patients with Encephalitis [PDF]
Clinical Infectious Diseases, 2005 We describe 4 patients with encephalitis due to possible reactivation of human herpesvirus 6 (HHV-6) infection who were enrolled in the California Encephalitis Project. All were immunocompetent and had HHV-6 loads determined in cerebrospinal fluid specimens. Tests for detection of HHV-6 should be considered for individuals with encephalitis.
Scott Schmid +7 more
openaire +2 more sources
Molecular Ecology Resources, EarlyView., 2023 Abstract Infectious diseases impact numerous organisms. Knowledge of host‐pathogen interactions and host responses to infection is crucial for conservation and management. Obtaining this knowledge quickly is made increasingly possible by a variety of genomic approaches, yet, for many species the bottleneck to understanding this, remains access to ...
Allison K. Miller +7 more
wiley +1 more source
Inibidores de Ebna1 como alvos para terapias associadas a oncogênese do herpesvírus humano 4 / Ebna1 inhibitors as targets for therapies associated with oncogenesis of human herpesvirus 4 [PDF]
Brazilian Journal of Health Review, 2021 Introdução: O vírus Epstein-Barr (EBV) ou Herpesvírus Humano 4 (HHV-4) está associado ao carcinoma nasofaríngeo e diferentes malignidades em pacientes infectados, as taxas de mortalidade destacam a necessidade de pesquisas direcionadas a oncogênese causada pelo vírus.
Padilha, Marcos Daniel Mendes +7 more
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CXC-Chemokine Receptor 4 Is Not a Coreceptor for Human Herpesvirus 7 Entry into CD4+T Cells [PDF]
Journal of Virology, 2000 ABSTRACTHuman herpesvirus 7 (HHV-7) is a T-lymphotropic virus which utilizes the CD4 receptor as its main receptor to enter the target cells. Hence, HHV-7 can interfere with human immunodeficiency virus type 1 (HIV-1) infection in CD4+T cells. It was recently suggested that the CXC chemokine receptor 4 (CXCR4), which was found to be a crucial ...
Dominique Schols +3 more
openaire +3 more sources
Replication of Bovine Herpesvirus Type 4 in Human Cells In Vitro [PDF]
Journal of Clinical Microbiology, 1998 ABSTRACTA reference strain (Movár 33/63) of bovine herpesvirus type 4 (BHV-4) was inoculated into 14 different human cell lines and five primary cell cultures representing various human tissues. BHV-4 replicated in two embryonic lung cell lines, MRC-5 and Wistar-38, and in a giant-cell glioblastoma cell culture.
openaire +3 more sources
Bovine Herpesvirus 4 Induces Apoptosis of Human Carcinoma Cell Lines In vitro and In vivo [PDF]
Cancer Research, 2005 Abstract The idea of using oncolytic viruses for the treatment of cancers was proposed a century ago. During the last two decades, viruses able to replicate specifically in cancer cells and to induce their lysis were identified and were genetically modified to improve their viro-oncolytic properties.
Laurence de Leval +4 more
openaire +3 more sources
Multiple sclerosis, human herpesvirus 4 and thyroid collision tumor: A case report
Experimental and Therapeutic Medicine, 2020 The role of interferon β-1b (IFNβ-1b), used for multiple sclerosis (MS) therapy, in cancer occurrence is uncertain. There is evidence supporting the role of human herpesvirus 4 [Epstein-Barr virus (EBV)] in thyroid cancer and MS. Simultaneous occurrence of papillary and medullary carcinomas is rare, and its association with MS in a young woman raises ...
Minerva Claudia Ghinescu +5 more
openaire +4 more sources
Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Open Reading Frame 4 Protein (Kaposica) Is a Functional Homolog of Complement Control Proteins [PDF]
Journal of Virology, 2003 ABSTRACTThe genome analysis of Kaposi's sarcoma-associated herpesvirus (KSHV) has revealed the presence of an open reading frame (ORF 4) with sequence homology to complement control proteins. To assign a function to this protein, we have now expressed this ORF using thePichiaexpression system and shown that the purified protein inhibited human ...
John Bernet +4 more
openaire +3 more sources