Results 151 to 160 of about 629,421 (295)

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Brentuximab Vedotin With Adriamycin, Vinblastine, and Dacarbazine for Patients Aged 18–59 Years With Untreated Advanced Stage Classical Hodgkin Lymphoma: The Largest Real‐Life Series From Southern Italy Cancer Centers

European Journal of Haematology, Volume 116, Issue 2, Page 174-184, February 2026.
ABSTRACT BV + AVD is increasingly used for frontline treatment of stage III/IV cHL. Young adults and adults (Ya&A) were the most common patients treated with BV + AVD in clinical trials but have not been studied in non‐trial settings. We conducted a real‐life study in secondary and tertiary cancer centers to evaluate the PFS in 18–59 years aged ...
Marco Picardi, Annamaria Vincenzi, Claudia Giordano, Novella Pugliese, Alessia Scarpa, Assunta Lombardi, Elena Vigliar, Giancarlo Troncone, Rosaria Cappiello, Massimo Mascolo, Giovanni Esposito, Maria Prastaro, Ciro Santoro, Roberta Esposito, Carlo Gabriele Tocchetti, Ciro Mainolfi, Rosa Fonti, Silvana Del Vecchio, Fabio Trastulli, Mario Annunziata, Rossella Iula, Catello Califano, Marianna Carchia, Marcello Persico, Alessia Salemme, Emanuele Nicolai, Andrea Soricelli, Marco Salvatore, Fabrizio Pane   +28 more
wiley   +1 more source

Grief‐Related Chest Pain: A Review, Conceptual Analysis, and Integrative Model

Psychophysiology, Volume 63, Issue 2, February 2026.
ABSTRACT Although the death of a loved one is a ubiquitous experience with chest pain a commonly reported symptom, grief‐related chest pain and particularly its physiological mechanisms remain under‐investigated. To address this gap, we adopted Rodger's approach to concept analysis to explore the psychoneuroimmunological mechanisms potentially linking ...
Sophia R. Evstigneev, Frank H. Wilhelm, George M. Slavich, David Blum, Annina Seiler   +4 more
wiley   +1 more source

Genetic diversity and geographic patterns of human herpesvirus 4 and 6

, 2017
This thesis focuses on Human herpesvirus 4 and 6, two ubiquitous viruses with a long list of putative disease associations, ranging from malignancies such as lymphomas and carcinomas to multiple sclerosis. To date, the relatively limited genetic data on these organisms hinders the understanding of their variability and their genetic structure at a ...
openaire   +1 more source

Impact of BoLA‐DRB3 Polymorphisms on Clonality of Bovine Leukaemia Virus‐Infected Cells of Cattle With Lymphoma

HLA, Volume 107, Issue 2, February 2026.
ABSTRACT Bovine leukaemia virus (BLV) infects cattle, integrates into the host genome as a provirus, and induces a persistent infection that remains asymptomatic but can cause leukaemia/lymphoma. Most BLV‐infected cell clones are created by massive depletion, and a few of these infected cell clones expand through the mitotic cycle, leading to the onset
Noriko Fukushi, Meripet Polat Yamanaka, Ryosuke Matsuura, Sonoko Watanuki, Susumu Saito, Yasunobu Matsumoto, Keisuke Fukumoto, Kazuyoshi Hosomichi, Jinliang Wang, Shin‐nosuke Takeshima, Yoko Aida   +10 more
wiley   +1 more source

European Code Against Cancer, 5th edition – cancer‐causing infections and related interventions

Molecular Oncology, Volume 20, Issue 1, Page 96-116, January 2026.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations related to cancer‐causing infections, namely H. pylori, HPV, HBV, HCV and HIV, positioned as recommendation number 12.
Catharina Johanna Alberts, Paul Bloem, Silvia de Sanjosé, Sophie Grabar, Marcis Leja, Peter Malfertheiner, Mojca Matičič, Francis Mégraud, Francesco Negro, Martyn Plummer, Maarten Schim van der Loeff, Graciela Balbín, Josefina Salazar, Hajo Zeeb, Ariadna Feliu, Erica D'Souza, David Ritchie, Carolina Espina, Silvia Franceschi   +18 more
wiley   +1 more source

Human Herpesvirus-8 Immediate-Early Region-4 Gene Locus [PDF]

, 2020
openaire   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

PBLD Orchestrates the STING‐Mediated Antiviral Immune Response and Autoimmune Diseases

Advanced Science, Volume 13, Issue 4, 19 January 2026.
During viral infection, PBLD expression is downregulated, thereby subverting host antiviral defenses and promoting viral replication. This study identifies PBLD as a positive regulator of STING‐induced type I interferon activation and delineated the molecular network underlying PBLD‐mediated antiviral immunity and autoimmune pathogenesis, highlighting ...
Peili Hou, Hongchao Zhu, Xiaonan Sun, Ni Zhang, Song Wang, Xuexing Zheng, Xiaoyun Wang, Yueyue Feng, Fuzhen Zhang, Xingyu Li, Rui Li, Xiaomeng Wang, Yuanyuan Han, Jun Wang, Chuanhong Wang, Xiaoyang Yao, Hongmei Wang, Hongbin He   +17 more
wiley   +1 more source

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, Volume 13, Issue 4, 19 January 2026.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source