Results 61 to 70 of about 629,421 (295)

Proteomic characterization of murid herpesvirus 4 extracellular virions. [PDF]

PLoS ONE, 2013
Gammaherpesvirinae, such as the human Epstein-Barr virus (EBV) and the Kaposi's sarcoma associated herpesvirus (KSHV) are highly prevalent pathogens that have been associated with several neoplastic diseases.
Sarah Vidick, Baptiste Leroy, Leonor Palmeira, Bénédicte Machiels, Jan Mast, Sylvie François, Ruddy Wattiez, Alain Vanderplasschen, Laurent Gillet   +8 more
doaj   +1 more source

EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives [PDF]

, 2019
Primary infection and pathogenesis of equine herpesvirus type 1 (EHV-1) require an intricate interaction of virus with the mucosal epithelium, mononuclear cells and the vascular endothelium.
Azab, Walid, Kamel, Mohamed, Osterrieder, Klaus, Pavulraj, Selvaraj   +3 more
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Mining metagenomes and metatranscriptomes unveils viruses associated with cutaneous squamous cell carcinoma in hematopoietic stem cell transplant recipients

Microbiology Spectrum
We investigated the presence of viral DNA and RNA in cutaneous squamous cell carcinoma (cSCC) tumor and normal tissues from nine individuals with a history of hematopoietic stem cell transplantation (HCT).
Jana K. Dickter, Yuqi Zhao, Vishwas Parekh, Huiyan Ma, Badri G. Modi, Wai-Yee Li, Saro H. Armenian, Xiwei Wu, Farah R. Abdulla   +8 more
doaj   +1 more source

Sequencing of bovine herpesvirus 4 v.test strain reveals important genome features

Virology Journal, 2011
Background Bovine herpesvirus 4 (BoHV-4) is a useful model for the human pathogenic gammaherpesviruses Epstein-Barr virus and Kaposi's Sarcoma-associated Herpesvirus.
Gillet Laurent, Vanderplasschen Alain, Lété Céline, Machiels Bénédicte, Palmeira Leonor   +4 more
doaj   +1 more source

Epstein-Barr Virus and Neurological Diseases

Frontiers in Molecular Biosciences, 2022
Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA virus that is ubiquitous in 90–95% of the population as a gamma herpesvirus.
Nan Zhang, Nan Zhang, Yuxin Zuo, Liping Jiang, Yu Peng, Xu Huang, Lielian Zuo   +6 more
doaj   +1 more source

Bovine herpesvirus 4-based vector delivering a hybrid rat/human HER-2 oncoantigen efficiently protects mice from autochthonous Her-2⁺mammary cancer [PDF]

OncoImmunology, 2015
The epidermal growth factor receptor 2 (HER-2) oncogene is a major target for the immunotherapy of breast cancer. Following up to the therapeutic success achieved with Her-2-targeting monoclonal antibodies, immune-prophylactic approaches directed against Her-2 have also been investigated taking into account, and trying to overcome, Her-2 self-tolerance.
Jacca, Sarah, ROLIH, VALERIA, QUAGLINO, Elena, Franceschi, Valentina, Tebaldi, Giulia, BOLLI, ELISABETTA, Rosamilia, Alfonso, Ottonello, Simone, CAVALLO, Federica, Donofrio, Gaetano   +9 more
openaire   +3 more sources

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

Features of Human Herpesvirus-6A and -6B Entry

Advances in Virology, 2012
Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj   +1 more source

Human Herpesvirus 6A Induces Dendritic Cell Death and HMGB1 Release without Virus Replication

Pathogens, 2021
Human herpesvirus 6A (HHV-6A) is a common virus that has important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity and are implicated in the pathogenesis of many human diseases, including infections.
Rasmus Gustafsson
doaj   +1 more source