Results 41 to 50 of about 13,539,459 (250)

Investigations on bovine herpesvirus 4 infections in cattle in Bulgaria

Bulgarian Journal of Veterinary Medicine, 2023
Cattle infected with BHV 4 show respiratory symptoms, gastrointestinal and postnatal genital disorders. The virus is a cofactor of bacterial infections.
R. Pashev
doaj   +1 more source

Proteomic characterization of bovine herpesvirus 4 extracellular virions. [PDF]

J Virol, 2012
ABSTRACT Gammaherpesviruses are important pathogens in human and animal populations. During early events of infection, these viruses manipulate preexisting host cell signaling pathways to allow successful infection. The different proteins that compose viral particles are therefore likely to have critical functions not only in viral structures
Lété C, Palmeira L, Leroy B, Mast J, Machiels B, Wattiez R, Vanderplasschen A, Gillet L.   +7 more
europepmc   +5 more sources

A single CD8+ T cell epitope sets the long-term latent load of a murid herpesvirus.

PLoS Pathogens, 2008
The pathogenesis of persistent viral infections depends critically on long-term viral loads. Yet what determines these loads is largely unknown. Here, we show that a single CD8+ T cell epitope sets the long-term latent load of a lymphotropic gamma ...
Sofia Marques, Marta Alenquer, Philip G Stevenson, J Pedro Simas   +3 more
doaj   +1 more source

Herpesvirus infections in ARVI episodes in children [PDF]

РМЖ. Мать и дитя, 2023
T.A. Ruzhentsova1,2, R.V. Popova3, A.A. Garbuzov1, E.K. Shushakova4, I.N. Khalyastov2,5, N.A. Meshkova6 1G.N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology of the Federal Service for the Oversight of Consumer Protection ...
T.A. Ruzhentsova, R.V. Popova, A.A. Garbuzov, E.K. Shushakova, I.N. Khalyastov, N.A. Meshkova   +5 more
doaj  

Search for the genome of bovine herpesvirus types 1, 4 and 5 in bovine semen [PDF]

Open Veterinary Journal, 2013
Bovine herpesvirus type 1 (BoHV-1) causes respiratory and reproductive disorders in cattle. Recently, bovine herpesvirus type 5 (BoHV-5) and bovine herpesvirus type 4 (BoHV-4) have been identified to be associated with genital disease. In this study, the
P.E. Morán, P.A. Favier, M. Lomónaco, M.C. Catena, M.L. Chiapparrone, A.C. Odeón, A.E. Verna, S.E. Pérez   +7 more
doaj  

E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation

Viruses, 2023
For productive infection and replication to occur, viruses must control cellular machinery and counteract restriction factors and antiviral proteins.
Jessica Oswald, Mathew Constantine, Adedolapo Adegbuyi, Esosa Omorogbe, Anna J. Dellomo, Elana S. Ehrlich   +5 more
doaj   +1 more source

NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]

, 2015
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J, Baquero, B, Jennifer J Wood, Adrian Whitehouse, Belinda Baquero-Pérez (706834), Hughes, DJ, David J Hughes, Whitehouse, A, Jackson, BR, Whitehouse, Adrian, Hughes, David John, Jackson, Brian R, Belinda Baquero-Pérez, Adrian Whitehouse (179093), Brian R Jackson, Brian R. Jackson (233567), Wood, JJ, Jennifer J. Wood (706833), David J. Hughes (167294), Baquero-Pérez, Belinda   +19 more
core   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Equine herpesvirus 1 and 4 infections: An update [PDF]

Veterinary Quarterly, 2002
Equine herpesvirus 1 (EHV1) and equine herpesvirus 4 (EHV4) are important ubiquitous equine viral pathogens, causing much damage to the horse industry. EHV1 strains are associated with respiratory disease, abortion, and paresis/paralysis, whereas EHV4 strains are predominantly associated with respiratory disease.
openaire   +2 more sources

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source