Results 51 to 60 of about 765 (178)

Comparison of proteins of simian herpesvirus aotus type 2 and bovine herpesvirus type 4

Journal of General Virology, 1991
Genomes of herpesvirus aotus type 2 (HVA-2) and bovine herpesvirus type 4 (BHV-4) have previously been shown to be closely similar. Moreover, preliminary serological data indicated that HVA-2 is antigenically related to BHV-4. To extend this study, structural components of four BHV-4 strains and HVA-2 were compared by SDS-PAGE, radioimmunoprecipitation
Dubuisson, J., Danyi, Sophie, Bublot, M., Pastoret, Paul-Pierre, Thiry, Etienne   +4 more
openaire   +3 more sources

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Late Cytomegalovirus Infections After Allogeneic Hematopoietic Cell Transplant

American Journal of Hematology, EarlyView.
ABSTRACT Graft versus host disease (GVHD) prophylaxis with posttransplant cyclophosphamide (ptCY) and cytomegalovirus (CMV) prophylaxis with letermovir have changed the clinical epidemiology of CMV infection. We studied the incidence, risk factors for, and outcomes of CMV infection after Day + 90 of allogeneic hematopoietic cell transplant (alloHCT ...
George L. Chen, Roland Bassett, Rohtesh S. Mehta, Betul Oran, Fareed Khawaja, Ella J. Ariza‐Heredia, Yosra Aljawai, Amanda Olson, May Daher, Portia Smallbone, Katayoun Rezvani, Partow Kebriaei, Uday Popat, Richard Champlin, Roy F. Chemaly, Elizabeth J. Shpall   +15 more
wiley   +1 more source

Next⁃generation sequencing technology in the diagnosis of five patients with human herpesvirus encephalitis/meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To evaluate the value of next⁃generation sequencing (NGS) of cerebrospinal fluid (CSF) in the diagnosis of human herpesvirus encephalitis/meningitis.
Ke JIN, Xiao-juan WANG, Hong-zhi GUAN, Ling-zhi QIN, Ya-zhen JIA, Ke-ke ZHOU, Hai-chang MA, Yue WANG, Fang WANG, Li XING, Wei LI   +10 more
doaj  

Potential Secondary Pathogenic Role for Bovine Herpesvirus 4 [PDF]

Journal of Clinical Microbiology, 2005
ABSTRACT Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with no clear disease association. Previous studies have demonstrated that macrophages can harbor persistent BoHV-4. We found that the addition of prostaglandin E2 (PGE2) to bovine macrophage cells persistently infected with BoHV-4 increases viral replication.
DONOFRIO, Gaetano, CAVIRANI, Sandro, FLAMMINI, Cesidio Filippo, VAN SANTEN V.   +3 more
openaire   +2 more sources

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

The role of mixed Mycoplasma and Herpesvirus infections in case of skin lesions in children

Детские инфекции (Москва), 2019
Numerous literature data show the role of mycoplasma infection in the development of non-respiratory lesions of various organs and systems, including the skin.
H. O. Kuvardina, F. S. Kharlamova, I. V. Polesko, O. V. Shamsheva, O. S. Ostapuschenko   +4 more
doaj   +1 more source

SEROREVELATION OF ANTIBODIES OF EQUINE HERPESVIRUS (EHV1/EHV4) IN SYRIA [PDF]

Assiut Veterinary Medical Journal, 2011
The objective of this study is, serological investigation of Epizootic Equine Abortion (EEA) or Equine Rhinopneumonitis (ER) Equine HerpesvirusMyeloencephalopathy(EHM) that know worldwide Equid herpesvirus (EHV type 1 and 4) in Syria. Equid herpesvirus 1
حازم الطويل, ، عبد الکريم قلب اللوز, ، محمد زهير الأحمد   +2 more
doaj   +1 more source