Results 91 to 100 of about 103,030 (240)

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, Filardi, M, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TORRISI, Maria Rosaria   +7 more
core   +1 more source

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

Immunohistochemical detection of the latent nuclear antigen-1 of the human herpesvirus type 8 to differentiate cutaneous epidemic Kaposi sarcoma and its histological simulators Detecção imuno-histoquímica do antígeno nuclear latente-1 do herpesvirus tipo 8 para diferenciar o sarcoma de Kaposi epidêmico cutâneo de seus simuladores histológicos

Anais Brasileiros de Dermatologia, 2013
Kaposi's sarcoma is the most common neoplasia diagnosed in AIDS patients and the expression of the human herpesvirus-8 (HHV-8) latent nuclear antigen-1 has been useful for its histological diagnosis.
Patricia Fonseca Pereira, Tullia Cuzzi, Maria Clara Gutierrez Galhardo   +2 more
doaj  

Human Herpesvirus-8 and Other Viral Infections, Papua New Guinea

Emerging Infectious Diseases, 2001
We studied residents of remote villages and the capital (Port Moresby) of Papua New Guinea to determine the distribution of human herpesvirus-8 (HHV-8) infection.
Giovanni Rezza, Robert T. Danaya, Theresa M. Wagner, Loredana Sarmati, Ifor L. Owen, Paolo Monini, Massimo Andreoni, Barbara Suligoi, Barbara Ensoli, Edoardo Pozio   +9 more
doaj   +1 more source

T cells from newly diagnosed multiple sclerosis patients have enhanced responsiveness to CD46 activation

Clinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods T cells from MS patients and non‐diseased symptomatic controls (SC) were activated in vitro with or without αCD46 antibody co‐stimulation.
Linda Sundvall, Litten S. Rossen, Vivien R. Schack, Bettina Bundgaard, Peter V. Rasmussen, Thor Petersen, Per Höllsberg   +6 more
wiley   +1 more source

Incidence of HHV‐6 Reactivation in Drug Reaction With Eosinophilia and Systemic Symptoms and Correlation With RegiSCAR Score: A Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
Allison Holt, Baraa Hijaz, Joseph Ebriani, Bethany Brumbaugh, Mike Westmeijer, Madeline E. DeWane, Michael Stephens, John Trinidad, Kevin Sheng‐Kai Ma, Steven T. Chen   +9 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Novel γ-2-Herpesvirus of the Rhadinovirus 2 Lineage in Gibbons

Emerging Infectious Diseases, 2004
We obtained 475 nucleotides of the DNA polymerase gene of a novel human herpesvirus 8 homolog sequence in a gibbon. The finding of this new gibbon virus, which clusters with a related chimpanzee virus in the rhadinovirus 2 genogroup, suggests the ...
Renan Duprez, Emmanuelle Boulanger, Yannick Roman, Antoine Gessain   +3 more
doaj   +1 more source

The Epstein-Barr Virus G-Protein-Coupled Receptor Contributes to Immune Evasion by Targeting MHC Class I Molecules for Degradation [PDF]

, 2009
Epstein-Barr virus (EBV) is a human herpesvirus that persists as a largely subclinical infection in the vast majority of adults worldwide. Recent evidence indicates that an important component of the persistence strategy involves active interference with
AB Rickinson, AD Hislop, AD Hislop, AJ Hirsch, Andrew Currin, B Grinde, B Park, Bryan D. Griffin, CA Joazeiro, CD Gregory, CJ Barnstable, Claire Shannon-Lowe, DA Thorley-Lawson, DA Thorley-Lawson, DH Lee, DT Purtilo, EJ Wiertz, EJ Wiertz, Emmanuel J. H. J. Wiertz, EW Hewitt, F Wang, FC Zhou, GW Wilkinson, H Hengel, H Rabin, HG Guo, HJ Delecluse, HM Long, J Wess, J Yuan, J Zuo, Jianmin Zuo, JL Stern, JP Johnson, K Ahn, K Ahn, K Janvier, Klaus Früh, L Coscoy, L Coscoy, LA Lampson, LS Young, M Greenberg, M Rowe, M Rowe, Maaike E. Ressing, Martin Rowe, ME Ressing, MH Fogg, MH Furman, MJ Clague, MM Rosenkilde, MR Kasper, NB Lubben, NJ Stam, NL Glosson, O Schwartz, P Rivailler, PG Stevenson, PJ Lehner, PS Beisser, R Aasland, R Chaudhuri, R Zeidler, RS Milne, S Bauer, S Drose, S Ishido, S Keating, S Le Gall, S Montaner, SJ Paulsen, SP Lee, SP Lee, TH Meyer, TR Jones, TR Jones, TY Yang, U Reusch, VA Pudney, Wendy A. Thomas, Z Wang   +81 more
core   +4 more sources

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, EarlyView.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source