Results 81 to 90 of about 84,279,697 (225)

Illness in Children Presenting to the Emergency Department After International Travel: A 10‐Year Retrospective Analysis From the University Hospital of Helsinki, Finland

Acta Paediatrica, EarlyView.
ABSTRACT Aim We characterized infections after international travel and identified predictors of severe infection to refine management. Methods We conducted a retrospective cross‐sectional analysis of children aged 0–18 years presenting to Helsinki University Hospital Emergency Department within 90 days of international travel between January 1, 2015 ...
Tuula Pelkonen, Svetlana Vakkilainen
wiley   +1 more source

Is human herpesvirus 8 infection more common in men than in women? an updated meta-analysis

BMC Infectious Diseases
Background Clinically, most patients with Kaposi's sarcoma (KS) are male, and several direct and indirect mechanisms may underlie this increased susceptibility in men, Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-
Haibo Gong, Shuai Zhang, Jinfa Dou, Jing Chen   +3 more
doaj   +1 more source

Multifocal Epithelioid Hemangioma With FOSB Overexpression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Epithelioid hemangioma (EH) is a benign vascular tumor that most commonly arises on the skin but may also occur in other anatomical locations, including deep soft tissue, bone, visceral organs, penis, and mucosal sites. A hallmark of EH is overexpression of FOS and FOSB, often resulting from various gene fusions.
Phuong Daniels, Aarush Kumar, Alexa Lum, Izabelle Bermudez, Shannon DeSilva, Jonathan Crane, Kristopher McKay   +6 more
wiley   +1 more source

First Diagnosed Case of Steroid-induced Kaposi's Sarcoma in Mongolia

Central Asian Journal of Medical Sciences, 2016
Objectives: Kaposi's sarcoma (KS) is a vascular neoplasm with four main types. We report the first diagnosed case of steroid-induced KS in a non-HIV patient in Mongolia.
Khandsuren Byamba, Ariunaa Munkhbayar, Oyuntsatsral Batsaikhan, Undram Sainzaya   +3 more
doaj   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

The FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas, Maria Pitou, Amalia Aggeli, Sotiris Varlamis, Theodora Choli‐Papadopoulou   +4 more
wiley   +1 more source

Prevalence of human herpesvirus 8 antibodies in the population of Belém, Pará, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2002
Serum samples from 497 children and adults inhabiting two neighbourhoods (Guamá and Terra Firme) in Belém, Pará, North Brazil were screened for the presence of human herpesvirus 8 (HHV-8) antibody using an enzyme-linked immunosorbent assay. An overall 16.
Ronaldo B. FREITAS, Maria Rute FREITAS, Alexandre C. LINHARES   +2 more
doaj  

Nano-Luciferase complementation assay of human herpesvirus 8 chemo/cytokine-receptor interactions

Scientific Reports
Some viruses encode proteins that mimic host chemokines and/or cytokines to modulate the host immune responses against infection. Human herpesvirus 8 (HHV-8), also termed Kaposi sarcoma-associated herpesvirus (KSHV), encodes three viral CC-type ...
Vikrant Palande, Richard B. S. Roden, Young Bong Choi   +2 more
doaj   +1 more source

Human Herpesvirus 8--the First Human Rhadinovirus

JNCI Monographs, 1998
Kaposi's sarcoma (KS)-associated herpesvirus, also known as human herpesvirus 8 (HHV-8), is the first known human member of the genus Rhadinovirus. It is regularly found by polymerase chain reaction in all forms of KS, in certain types of Castleman's disease, and in body cavity-based B-cell lymphoma.
F, Neipel, J C, Albrecht, B, Fleckenstein   +2 more
openaire   +2 more sources

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

The FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon, Kyra Swildens, Vera M. Kalscheuer, Cristina Gontan, Francisco Bustos   +4 more
wiley   +1 more source

NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]

, 2015
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J, Baquero, B, Jennifer J Wood, Adrian Whitehouse, Belinda Baquero-Pérez (706834), Hughes, DJ, David J Hughes, Whitehouse, A, Jackson, BR, Whitehouse, Adrian, Hughes, David John, Jackson, Brian R, Belinda Baquero-Pérez, Adrian Whitehouse (179093), Brian R Jackson, Brian R. Jackson (233567), Wood, JJ, Jennifer J. Wood (706833), David J. Hughes (167294), Baquero-Pérez, Belinda, Baquero-Pérez Belinda, Hughes David J., Jackson Brian R., Wood Jennifer J., Whitehouse Adrian, Hughes, David John; id_orcid   +25 more
core   +1 more source