Results 91 to 100 of about 585,481 (213)

New Insights Into Immunomodulatory Strategies for Drug Hypersensitivity Reactions: An EAACI Task Force Report

open access: yesClinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Drug hypersensitivity reactions (DHRs) are a global health concern and remain challenging to investigate owing to the heterogeneity of endotypes and phenotypes, as well as the lack of standardized biomarkers. Until recently, strict drug avoidance was the only management strategy for severe DHRs.
Ana Maria Copaescu   +13 more
wiley   +1 more source

Human Herpesvirus 8 in Healthy Blood Donors, Argentina

open access: yesEmerging Infectious Diseases, 2010
Celeste L. Pérez   +3 more
doaj   +1 more source

Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review

open access: yesEuropean Journal of Immunology, Volume 56, Issue 8, August 2026.
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato   +2 more
wiley   +1 more source

TAFRO syndrome: current perspectives

open access: yesJournal of Blood Medicine, 2018
Kentaro Sakashita,1,2 Kengo Murata,2 Mikio Takamori2 1Department of Internal Medicine, Tokyo Metropolitan Matsuzawa Hospital, 2Department of Respiratory Medicine, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan Abstract: Multicentric Castleman’
Sakashita K, Murata K, Takamori M
doaj  

Can epilepsy be predicted after the first febrile seizure? Insights from machine learning of postictal EEG

open access: yesEpileptic Disorders, Volume 28, Issue 4, Page 1150-1158, August 2026.
Abstract Objective Febrile seizures (FS) are the most common seizures in childhood, yet identifying children at risk of developing epilepsy after the first FS remains challenging. We aimed to evaluate the prognostic potential of machine learning (ML) algorithms applied to post‐febrile seizure electroencephalography (EEG) recordings.
Boran Şekeroğlu   +7 more
wiley   +1 more source

Clinical‐Stage Nanatinostat Triggers Productive Epstein‐Barr Virus Lytic Replication

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT A phase 1b/2 study of the all‐oral “kick‐and‐kill” combo nanatinostat + valganciclovir (nana‐val) showed a ~40% overall response rate in patients with relapsed/refractory Epstein‐Barr virus (EBV)‐associated lymphomas. Despite the promising results in these difficult‐to‐treat cancers, there is little known about the effects of nanatinostat on ...
Ibukun A. Akinyemi   +6 more
wiley   +1 more source

A Snapshot of the UK Blood Donor Plasma Virome: A Retrospective Cross‐Sectional Cohort Study

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Estimates of population prevalence and genetic diversity of bloodborne viruses in healthy humans are essential to support population‐scale monitoring for transfusion transmission risk. In the UK and globally, blood donations are routinely screened for a limited number of high‐consequence pathogens, but the full composition of the plasma virome
Kai Kean   +12 more
wiley   +1 more source

Associations of Inherited Chromosomally‐Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Zhong Qiya   +5 more
wiley   +1 more source

Nucleotide Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao   +7 more
wiley   +1 more source

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