Results 81 to 90 of about 608,679 (284)

Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus

Nature Communications, 2019
Viral control of mitochondrial quality and content has emerged as an important mechanism for counteracting the host response to virus infection. Despite the knowledge of this crucial function of some viruses, little is known about how herpesviruses ...
Mai Tram Vo, Barbara J Smith, J. Nicholas, Y. Choi   +3 more
semanticscholar   +1 more source

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

Eye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang, Xiaoyu Song, Fengxin Yang, Huhuifen He, Kun Zhao, Jingjing Qiu, Limei Cui, Qiang Zhang, Limei Liu, Yan Sun   +9 more
wiley   +1 more source

Human Herpesvirus 8-Encoded Cytokines [PDF]

Future Virology, 2010
Human herpesvirus (HHV)-8, also called Kaposi's sarcoma-associated herpesvirus, was discovered in 1994 and was rapidly sequenced, revealing several unique and surprising features of its genetic makeup. Among these discoveries was the identification of the first viral homolog of IL-6 and three CC/beta-chemokine ligands (viral CCL-1, -2 and -3), not ...
openaire   +3 more sources

Endemic Kaposi sarcoma in HIV-negative children and adolescents: an evaluation of overlapping and distinct clinical features in comparison with HIV-related disease

Infectious Agents and Cancer, 2018
Background Endemic Kaposi sarcoma (KS) was first described in African children over fifty years ago, but has recently been overshadowed by HIV-related disease.
Nader Kim El-Mallawany, Jimmy Villiera, William Kamiyango, Erin C. Peckham-Gregory, Michael E. Scheurer, Carl E. Allen, Casey L. McAtee, Alejandra Legarreta, Dirk P. Dittmer, Carrie L. Kovarik, Elizabeth Y. Chiao, Stephen C. Martin, Nmazuo W. Ozuah, Parth S. Mehta, Peter N. Kazembe   +14 more
doaj   +1 more source

Current Progress in Targeting Human Cytomegalovirus Infection

iLABMED, EarlyView.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Herpes Simplex Virus Type 1 Infection: Features of immune surveillance and antiviral resistance [PDF]

, 2013
__Abstract__ The family of Herpesviridae is highly disseminated in the animal world, with a wide range of host species. Because most animal species have at least one herpesvirus, the number of herpesviruses in nature is likely to exceed by far the ...
Velzen, M. (Monique) van
core  

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]

, 2013
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad, B. Tolani, Ballon, Benhamou, Bower, Bren, C. Graham, Chang, Chaudhary, Chugh, Delmore, Dong, Du, Dupin, Dupin, Eeva, Eeva, Field, Gerondakis, Guasparri, H. Matta, H. Yi, Hassman, Herzog, Lee, Liu, Madureira, Matta, Matta, Matta, Matta, Mineva, Nador, Niiro, P. M. Chaudhary, Parravicini, Punj, Schauer, Soulier, Sun, Sun, Sun, Thome, Vrzalikova, Waterston, Wu, Wu, Wu, Y. Suo, Y. Yang, Yang, Yang, Young, Zhao   +53 more
core   +1 more source

Novel Human Herpesvirus 8 Subtype D Strains in Vanuatu, Melanesia

Emerging Infectious Diseases, 2007
We show human herpesvirus 8 with diverse molecular subtype D variants to be highly endemic among the Ni-Vanuatu population. Most K1 genes were nearly identical to Polynesian strains, although a few clustered with Australian or Taiwanese strains.
Olivier Cassar, Philippe V. Afonso, Sylviane Bassot, Sabine Plancoulaine, Renan Duprez, Corinne Capuano, Myriam Abel, Paul M.V. Martin, Antoine Gessain   +8 more
doaj   +1 more source

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma.

Proceedings of the National Academy of Sciences of the United States of America, 1999
Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi's sarcoma (KS), multicentric Castleman's disease (MCD), and primary effusion lymphoma (PEL). The universal presence of HHV-8 in early KS has not yet been shown.
Nicolas Dupin, C. Fisher, P. Kellam, S. Ariad, M. Tulliez, N. Franck, E. V. Marck, D. Salmon, I. Gorin, J. Escande, R. Weiss, K. Alitalo, C. Boshoff   +12 more
semanticscholar   +1 more source

Paediatric acute liver failure: A prospective, nationwide, population‐based surveillance study in Germany

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Paediatric acute liver failure (PALF) is a rare but life‐threatening condition, yet comprehensive epidemiological data in Germany are lacking. Our study aimed to systematically analyse incidence, aetiology, and outcome of PALF in Germany.
Dominic Lenz, Muhammad Abdulaziz, Bianca Peters, Matias Wagner, Lea D. Schlieben, Victor M. Corman, Ulrich Baumann, Philip Bufler, Tal Dattner, Rainer Ganschow, Kristin Genzel, Nicole Hammann, Steffen Hartleif, Bianca Hegen, Stephan Henning, André Hoerning, Martin Jankofsky, Norman Junge, Simone Kathemann, Birgit Knoppke, Martina Kohl‐Sobania, Martin Laass, Elke Lainka, Eberhard Lurz, Michael Melter, Hanna Müller, Denisa Pilic, Markus Ries, Lisa Schiefele, Tobias Schwerd, Ekkehard Sturm, Mechtild Wegner, Michael S. Urschitz, Sven F. Garbade, Daniel Wenning, Christian Drosten, Alexander Fichtner, Stefan Kölker, Georg F. Hoffmann, Holger Prokisch, Christian Staufner   +40 more
wiley   +1 more source