Results 111 to 120 of about 47,471 (249)

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 325-347, January 2026.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro   +2 more
wiley   +1 more source

Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication

open access: yesCell Reports, 2019
Summary: To ensure a successful infection, herpesviruses have developed elegant strategies to counterbalance the host anti-viral responses. Sterile alpha motif and HD domain 1 (SAMHD1) was recently identified as an intrinsic restriction factor for a ...
Kun Zhang, Dong-Wen Lv, Renfeng Li
doaj   +1 more source

Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G [PDF]

open access: yes, 1999
Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding.
Bjorkman, Pamela J.   +5 more
core   +1 more source

AIRE's Complex Role Beyond Promiscuous Gene Expression

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Central tolerance, established in the thymus, ensures T cells are nonreactive to self‐antigens while maintaining a functional immune repertoire. Medullary thymic epithelial cells (mTECs) and thymic dendritic cells (DCs) play a crucial role in this mechanism by orchestrating the selection and deletion of autoreactive thymocytes, a process ...
Pärt Peterson
wiley   +1 more source

Evaluation of Laboratory Techniques for the Diagnosis of Leptospira‐Associated Equine Recurrent Uveitis (ERU) With Focus on the Goldmann‐Witmer Coefficient

open access: yesVeterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT Purpose To evaluate different laboratory procedures for determining the etiologic diagnosis of equine recurrent uveitis regarding intraocular infection with Leptospira spp. and to establish a diagnostic guideline. Material and Methods Eighty horses with a history of ERU were ophthalmologically examined.
Lena Kirmse   +3 more
wiley   +1 more source

A neurotropic herpesvirus infecting the gastropod, abalone, shares ancestry with oyster herpesvirus and a herpesvirus associated with the amphioxus genome

open access: yesVirology Journal, 2010
Background With the exception of the oyster herpesvirus OsHV-1, all herpesviruses characterized thus far infect only vertebrates. Some cause neurological disease in their hosts, while others replicate or become latent in neurological tissues.
Sawbridge Tim   +6 more
doaj   +1 more source

Herpesviruses. Part 1 [PDF]

open access: hybrid, 2020
R. S. Nazaryan   +5 more
openalex   +1 more source

Rapid taxonomic categorization of short, abundant virus sequences for ecological analyses

open access: yesEcology and Evolution
Public health concerns about recent viral epidemics have motivated researchers to seek novel ways to understand pathogen infection in native, wildlife hosts. With its deep history of tools and perspectives for understanding the abundance and distribution
Anna R. Sjodin   +3 more
doaj   +1 more source

Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses [PDF]

open access: gold, 2020
Gurpreet Brar   +11 more
openalex   +1 more source

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